产妇及其新生儿血浆长链脂肪酸组成分析  

Analysis of Long Chain Fatty Acids Composition of Maternal and Neonatal Plasma.

作　　者：李红娟[1] 刘德华[1] 

机构地区：[1]山西医科大学儿少卫生教研室，太原 030001

出　　处：《中国公共卫生》2001年第1期6-7,共2页Chinese Journal of Public Health

基　　金：山西省自然科学基金

摘　　要：目的　分析了 2 0名正常产妇静脉血及其新生儿脐血血浆中脂肪酸组成。方法　采用气相色谱法。结果　脐血中廿二碳六烯酸 (DHA)、花生四烯酸 (AA)含量显著高于母血 (P<0 0 0 1) ;脐血中亚油酸 (LA)含量为母血的 1/ 5 ,而α 亚麻酸(α LNA)含量脐血与母血无显著差异 ;脐血中DHA含量与母血中DHA含量高相关 (r2 =0 76 ,P <0 0 0 1) ,脐血中AA与母血中AA、LA含量均显著性相关 (P <0 0 5 ,P <0 0 0 1) ,结论　母血中DHA、AA可优先通过胎盘满足胎儿需要 ;胎儿对n - 3和n -Objective This study analysed plasmal long chain fatty acids composition of 20 healthy.Method Normal perinatal maternal blood(M) and their umbilical cord blood(U) by gasliquid chromatography.Results Arachidonic acid(AA) and docosahexaenoic acid(DHA)contents of U were significantly higher than M(P<0 001);DHA was highly related to DHA level of M(r\+2=0 76,P<0 001);AA content of U was related to AA and linoleic acid(LA) level of M(P<0 05,P<0 001).Conclusions The developong fetus migtht be preferentially supplied with DHA via the placenta;The usage of n-3 and n-6 fatty acid in fetus might be different.

关 键 词：甘二碳六烯酸 花生四烯酸 产妇 新生儿 血浆 

分 类 号：R446.112[医药卫生—诊断学]