Voltammetric Determination of Epinephrine in the Presence of Uric Acid Based on Aminated Graphene and Ag NPs Hybrid Membrane Modified Electrode  

作　　者：XU Huanhuan WANG Xueliang CHEN Rong YU Zhangyu 

机构地区：[1]Department of Chemistry and Chemical Engineering, Qufu Normal University, Qufu 273165, P.R.China [2]Department of Chemistry and Chemical Engineering, Heze University, Heze 274015, P.R.China

出　　处：《Chemical Research in Chinese Universities》2014年第2期205-210,共6页高等学校化学研究（英文版）

基　　金：Supported by the National Natural Science Foundation of China（No.21105023） and the Natural Science Foundation of Shandong Province,China（Nos.BS2013HZ027,ZR2009BM003）.

摘　　要：A hybrid membrane consisted of aminated graphene and Ag nanoparticles（Ag NPs） was prepared on the surface of glassy carbon electrode（GCE） by cyclic voltammetry（CV） with aminated graphene（GR-NH2） as matrix for immobilizing Ag NPs.The morphology and electrochemical properties of this hybrid membrane were characterized by scanning electron microscopy（SEM） and CV,respectively,and on this membrane,the voltammetric behaviors of epinephrine（EP） were studied in detail.The membrane exhibited excellent eletro-catalytic activities for the redox of EP,and could resolve the electrochemical response of EP and uric acid（UA） into two oxidation peaks.The peak current of EP was linear with its concentration in the ranges of 0.916-18.3 μmol/L and 18.3-184 μmol/L.The detection limit was 2.0 nmol/L（S/N=3）.The proposed modified electrode retained the advantages of easy fabrication,high sensitivity and good repeatability for the determination of EP.A hybrid membrane consisted of aminated graphene and Ag nanoparticles（Ag NPs） was prepared on the surface of glassy carbon electrode（GCE） by cyclic voltammetry（CV） with aminated graphene（GR-NH2） as matrix for immobilizing Ag NPs.The morphology and electrochemical properties of this hybrid membrane were characterized by scanning electron microscopy（SEM） and CV,respectively,and on this membrane,the voltammetric behaviors of epinephrine（EP） were studied in detail.The membrane exhibited excellent eletro-catalytic activities for the redox of EP,and could resolve the electrochemical response of EP and uric acid（UA） into two oxidation peaks.The peak current of EP was linear with its concentration in the ranges of 0.916-18.3 μmol/L and 18.3-184 μmol/L.The detection limit was 2.0 nmol/L（S/N=3）.The proposed modified electrode retained the advantages of easy fabrication,high sensitivity and good repeatability for the determination of EP.

关 键 词：Ag nanoparticle（Ag NP） Aminated graphene（GR-NH2） Epinephrine（EP） Uric acid（UA） Cyclic voltammetry（CV） 

分 类 号：O646.54[理学—物理化学] Q577[理学—化学]