Evaluation on Antisperm Antibody in Infertile Men with Oligoasthenoteratozoospermia  

作　　者：Yi-chao XU Jing LI Wei-bao LIANG Wei-jie ZHU 

机构地区：[1]Department of Urology, the First Affiliated Hospital, Jinan University [2]Department of Pathophysiology, Medical College, Jinan University [3]Department of Developmental and Regenerative Biology, College of Life Science and Technology, Jinan University

出　　处：《Journal of Reproduction and Contraception》2014年第1期49-53,共5页生殖与避孕（英文版）

摘　　要：To evaluate the level of antisperm antibody （ASA） in infertile men with oligoasthenoteratozoospermia （OAT）. Methods Forty-six infertile men with OAT were enrolled into this study. Sperm samples were screened by the direct immunobead test for ASA type IgG and lgA according to the WHO laboratory manual. Results Of the 46 patients with OAT assessed for ASA-IgG, 2 had immunobead binding which were 22% and 27%, respectively, and the sub-positive rate was 4.3%. No case had the clinical positive level according to the WHO criteria （ ≥ 50% of the motile sperm with immunobead binding）. ASA-IgA was not detected in all cases. Conclusion A significant incidence or high level of ASA could not be found in infertile men with OAT, which suggests that ASA is not associated with the pathogenesis of infertile men with OAT.To evaluate the level of antisperm antibody （ASA） in infertile men with oligoasthenoteratozoospermia （OAT）. Methods Forty-six infertile men with OAT were enrolled into this study. Sperm samples were screened by the direct immunobead test for ASA type IgG and lgA according to the WHO laboratory manual. Results Of the 46 patients with OAT assessed for ASA-IgG, 2 had immunobead binding which were 22% and 27%, respectively, and the sub-positive rate was 4.3%. No case had the clinical positive level according to the WHO criteria （ ≥ 50% of the motile sperm with immunobead binding）. ASA-IgA was not detected in all cases. Conclusion A significant incidence or high level of ASA could not be found in infertile men with OAT, which suggests that ASA is not associated with the pathogenesis of infertile men with OAT.

关 键 词：antisperm antibody （ASA） SPERM oligoasthenoteratozoospermia （OAT） INFERTILITY 

分 类 号：R698.2[医药卫生—泌尿科学]