伏九敷贴防治小儿反复呼吸道感染临床观察及免疫功能分析  

Clinical Observation of Prevention and Treatment for Children's Recurrent Respiratory Tract Infection in Summer and Winter by Acupoint Application Therapy with Herbal Ion Penetration and Trend of sIgA

作　　者：霍莉莉[1] 宣小平[1] 虞坚尔[1] 卢伯良 夏以琳[1] 陈莹[1] 李华[3] 

机构地区：[1]上海中医药大学附属市中医医院,上海200071 [2]上海市松江区方塔中医医院,上海201600 [3]上海市嘉定区中医医院,上海201800

出　　处：《辽宁中医杂志》2014年第4期701-705,共5页Liaoning Journal of Traditional Chinese Medicine

基　　金：上海市卫生局科研基金课题(2009s011);同济大学"中医大师传承人才培养项目"[国中医药函2008(185)]

摘　　要：目的:观察冬夏伏九离子仪导入中药穴位敷贴外治法防治小儿反复呼吸道感染的临床疗效。方法:采用治疗前后自身对照法,多中心临床收集120例反复呼吸道感染患儿,借助离子导入仪,进行中药穴位敷贴,随访1年,观察治疗前、后呼吸道感染的疾病计分、疾病类型、全年发病次数、感染期平均治疗天数、感染期给药途径、中医症状及体征的变化,并检测患儿治疗前后唾液sIgA。通过比较上述指标的差异,分析该法对小儿反复呼吸道感染的疗效及作用途径。结果:①该法总有效率78.0%;②与治疗前相比,治疗后疾病计分明显下降(P<0.01);③性别与疗效有相关性(P<0.05);④治疗后疾病类型变化单纯型疾病改善优于复杂型(P<0.05);⑤治疗后上呼吸道感染、支气管炎和肺炎的全年发病次数减少(P<0.01);感染期平均治疗天数明显缩短(P<0.01);感染期给药途径由静滴向口服转变(P<0.01);⑥多汗、眠差、面色差及舌象异常明显改善(P<0.05);⑦唾液sIgA明显升高(P<0.001)结论:冬夏同治离子仪导入中药穴位敷贴外治法是防治小儿反复呼吸道感染的有效手段。该法可减少疾病计分、改善疾病类型、减少发病次数、缩短感染期治疗天数、改善感染期给药途径、改善多汗、眠差、面色异常、舌象异常症状,对升高唾液sIgA作用较持续。Objective ：To observe the clinical effect of treating children＇s recurrent respiratory tract infections （RRTI） by acu- point application with herbal ion penetration therapy in summer and winter. Methods ： This intervention was designed as a self con- trol trial. It selected 120 cases of children patients who met the inclusion criteria in multiple centers and treated them with the ex- ternal treatment,following up for 1 year. Before and after the treatment, it was to observe the disease scores, types of diseases, year-average number of days of treatment during infection period, the ways of drug delivery in infection period, signs and symptoms of TCM, and to detect the salivary sIgA. By comparing the difference between the above metrics, the curative effect and the func- tion were analyzed. Results ：（~）The total effective rate was 78.0%. （~）The disease score was significantly decreased after treatment （P 〈 0.01 ）. （3）The age, disease types and course of disease had no significant correlation with curative effect （P 〉 0.05）, but the gender had. （4）The simplex disease type change improved after treatment, superior to the complexity one（ P 〈 0.05 ）. （5）After treatment, the upper respiratory tract infections （ URTI ）, bronchitis and pneumonia annual incidence were decreased （ P 〈 0.01 ）. In the infection period, the average number of days of treatment were significantly reduced （ P 〈 0.01 ） and ways of drug delivery changed from the static drops to oral administration （P 〈 0.01 ）. （6）The sweat, sleeping, face and tongue symptoms were improved significantly （P 〈0.05）. （7）The salivary slgA was increased （P 〈0.01 ）. Conclusion ：Acupoint application with herbal ion pene- tration therapy for children＇s RRTI in summer and winter is an effective clinical treatment in the prevention and treatment of in- fantile RRTI. The method could reduce disease scores, improve disease types, reduce recurrence times and shorten days of treat- men

关 键 词：反复呼吸道感染 穴位敷贴 SIGA 重复测量 多重比较 

分 类 号：R56[医药卫生—呼吸系统]