中药糖通饮方对早期糖尿病肾病患者血清血管内皮生长因子的影响  被引量:6

The effect of traditional Chinese medicine Tangtong Yin on VEGF in patients with early stage of diabetic nephropathy

在线阅读下载全文

作  者:王和强[1,2] 张太坤[1] 符莹[1] 廖信茜[1] 周湧[1] 邓淦林[1] 邓少奇[1] 

机构地区:[1]东莞市太平人民医院,广东东莞523900 [2]东莞市康复医院,广东东莞523119

出  处:《长春中医药大学学报》2014年第2期298-300,共3页Journal of Changchun University of Chinese Medicine

基  金:广东省中医药局建设中医药强省科研课题(粤中医[20122057])

摘  要:目的观察中药糖通饮方对早期糖尿病肾病患者血清血管内皮生长因子(VEGF)的影响。方法将80例患者随机分为对照组40例,治疗组40例,对照组予以常规治疗,治疗组在对照组治疗基础上加用中药糖通饮方(药用黄芪、地骨皮、熟地黄、山药等)治疗,治疗12周,检测治疗前后患者VEGF、空腹血糖(FBG)、餐后2 h血糖(2Hbg)、尿素氮(BUN)及肌酐(Scr),计算内生肌酐清除率(Ccr)等指标。结果治疗后,治疗组较对照组VEGF、FBG、2hBG、Scr显著下降,Ccr显著升高(P<0.05或P<0.01)。结论中药糖通饮方治疗早期糖尿病肾病能改善患者肾功能,降低VEGF,对肾脏病变具有保护作用。Objective To observe the effect of the Chinese herb Tangtong Yin (TRY) on VEGF in patients with early stage of diabetic nephropathy. Methods 80 patients were randomly divided into two groups: control group( n = 40) and treatment group (n = 40). The control group was given conventional treatment. The treatment group was added Tangtong Yin (Astra- galus, Lycium chinense, prepared rhizome of rehmannia, Chinese yam, etc. ) besides the conventional treatment. The patients received 12-week treatment. VEGF, FBG,2Hbg, Bun, Ccr,Scr and other indicators were detected before and after the treat- ment. Results VEGF, FBG,2Hbg and Scr of the treatment group were distinctly decreased compared with those of the con- trol group, the Ccr and INS were distinctly increased compared with those of the control group ( P 〈 0.05 or P 〈 0.001 ). Conclusion TI'Y for patients with early stage of diabetic nephropathy can improve the renal function, decrease VEGF and has a protective effect on renal lesions.

关 键 词:糖尿病肾病 中医药疗法 中药糖通饮方 血管内皮生长因子 

分 类 号:R255.4[医药卫生—中医内科学]

 

参考文献:

正在载入数据...

 

二级参考文献:

正在载入数据...

 

耦合文献:

正在载入数据...

 

引证文献:

正在载入数据...

 

二级引证文献:

正在载入数据...

 

同被引文献:

正在载入数据...

 

相关期刊文献:

正在载入数据...

相关的主题
相关的作者对象
相关的机构对象