46例老年妇女糖尿病患者的骨量改变  

Effect of Type Ⅱ Diabetes Mellitus on Bone Mineral Density in Elderly Females

作　　者：刘靖[1] 

机构地区：[1]宁夏医学院附属医院内分泌科,银川750004

出　　处：《宁夏医学院学报》2001年第1期14-15,共2页Journal of Ningxia Medical College

摘　　要：目的 :研究Ⅱ型糖尿病时的老年妇女骨密度变化。方法 :应用单光子骨矿物密度仪测量 46例老年妇女Ⅱ型糖尿病患者及 12 2例健康对照者的尺桡骨密度 (BMD)。结果 :Ⅱ型糖尿病组BMD较对照组高 (P <0 0 5 )。两组骨量减少检出率无显著性差异。年龄、绝经年限与糖尿病患者BMD呈负相关 (P <0 0 1)。糖尿病骨量减少组的视网膜病变、肾病例数显著高于骨量正常组。而血清胰岛素 (INS)水平显著低于骨量正常组 (P <0 0 1)。结论 :老年妇女Ⅱ型糖尿病患者的BMD是增高的。Objective:To investigate the effect of non-insulin-dependent diabetes mellitus on bone mineral density (BMD) in older women.Methods:single photoabsorptiometer was utilized to determine the BMD of Ulna and Radius in older women with type Ⅱ diabetes (n=46) and in heallthy controls (n=122).Results:BMD in type Ⅱ diabetes patient was significantly higher than that of controls (P<0.05).No significant difference was found in morbidity of osteopenia between diabetes patient and controls.BMD was negatively correlated with age and years since menopause (P<0 01).The morbidity of retinopathy and nephropathy was significantly higher and insulin content in blood was significantly lower in diabetes women with osteopenia than those of diabetes women with normal BMD (P<0.01).Conclusions:These results suggest that BMD in older women with type Ⅱ diabetes is increased.

关 键 词：Ⅱ型糖尿病 老年妇女 骨密度 单光子骨矿物密度仪 

分 类 号：R587.1[医药卫生—内分泌]