模拟动能武器致伤犬双后肢后部分代谢和生化指标的变化  

Changes of several metabolic and biochemical indices of dogs with both hindlimbs injured by imitative kinetic weapon

作　　者：陈向阳[1] 李兵仓[1] 王建民[1] 张良潮[1] 吴国萍[1] 陈菁[1] 陈志强[1] 

机构地区：[1]第三军医大学附属大坪医院野战外科研究所第六研究室,重庆400042

出　　处：《第三军医大学学报》2001年第2期163-165,共3页Journal of Third Military Medical University

基　　金：全军"九五"面上课题!(98M0 87)

摘　　要：目的　探讨动能武器致伤犬双后肢后部分代谢及生化指标的变化特点。方法　 12只动物分为常规武器致伤组 (I组 ,n =3 )和动能武器致伤组 (n =9) ,动能武器致伤组按致伤动能的大小进一步分为II、III、IV组 ,每组各 3只。致伤犬双后肢 ,观察致伤前后血浆Na+ 、Ca2 + 、K+ 、淀粉酶 (AMY)、乳酸脱氢酶 (LDH)、肌酸激酶 (CK)、血糖水平以及血清胰岛素、三碘甲腺原氨酸 (T3 )、促甲状腺素 (TSH)水平的变化。结果　①动能武器致伤组动物局部伤情及远隔脏器损伤明显重于常规武器组。②动能武器致伤后动物血糖水平显著高于伤前 (P <0 .0 5 ) ,常规武器组相差不显著 ;CK水平在动能武器致伤组伤后明显高于常规武器组 (P <0 .0 5 )。③血清TSH水平在动能武器致伤组伤后明显增高 (P <0 .0 5 ) ,但常规武器组相差不显著。结论　动能武器不仅使局部受损严重 ,还能造成比常规武器更加严重的远隔器官损伤以及更加明显的生化、代谢指标改变。Objective To explore the characteristics of the changes of several metabolic and biochemical indices in dogs with both hindlimbs injured by kinetic weapon. Methods 12 animals were divided into 4 groups (Group Ⅰ, injured by regular weapon; Group Ⅱ,Ⅲ,Ⅳ injured by imitative kinetic weapons with different energy respectively). Levels of plasma Na +,Ca 2+ ,K + glucose, AMY, LDH, CK and serum T 3,insulin,TSH were determined before and after injured. Results ①Local wounding conditions and distant organs' injuries in group Ⅱ,Ⅲ, and Ⅳ were more serious than those in group Ⅰ. ②Levels of plasma glucose in group Ⅱ,Ⅲ and Ⅳ were inereased significantly after injury than before( P <0.05), but not in group Ⅰ. Levels of Na +,Ca 2+ ,K +,AMY,LDH in 4 groups had similar changes after injury while levels of CK in group Ⅱ,Ⅲ and Ⅳ were inereased significantly than that in group Ⅰ ( P <0.05). ③After injury, levels of T 3 in serum of all animals showed a decreased tendency and that of insulin decreased more significantly ( P <0.05). There was no difference between every two groups. Levels of TSH in group Ⅱ,Ⅲ and Ⅳ were increased significantly after injured than before ( P <0.05), but not in group Ⅰ. Conclusion Not only local severe injury but also more serious injury in distant organs and more obvious changes of metabolic and biochemical indices can be induced by kinetic weapons than regular weapons.

关 键 词：动能武器 犬 生化 代谢 双后肢损伤 

分 类 号：R826.5[医药卫生—临床医学] R827