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作 者:郭艺[1] 谭理连[1] 黄成辉[2] 李汉文[1] 叶素贞[1]
机构地区:[1]广州医科大学附属第二医院放射科,广东广州510260 [2]广州医科大学附属第二医院风湿内科,广东广州510260
出 处:《中国CT和MRI杂志》2014年第2期86-89,共4页Chinese Journal of CT and MRI
摘 要:目的观察手腕部磁共振成像(MRI)分析中西医结合治疗类风湿性关节炎的疗效。方法将临床确诊类风湿性关节炎患者46例分为两组:中西医结合治疗组(21例)和西医对照组(25例),治疗前、后均进行MRI平扫+增强检查及X线检查,分析比较治疗前后临床效果、MRI及X线影像学改变。结果中西医结合治疗组有效率为95%,西医对照组有效率为72%,两组疗效差异有统计学意义(P<0.05)。治疗后MRI显示增厚的滑膜厚度减小、滑膜及血管翳强化程度减弱、骨髓水肿减轻或消失、关节积液减少、骨和软骨侵蚀无增加。治疗前后的类风湿性关节炎患者X线检查对比无明显变化。结论中西医结合治疗类风湿性关节炎较单纯西医治疗疗效好。MRI能有效评价类风湿性关节炎治疗效果,临床上可推广应用。Objective Analyze therapeutic effect of combined treatment of traditional Chinese medicine and western medicine for Rheumatoid arthritis(RA)via MRI observation. Methods 46 patients clinically diagnosed as RA were divided into 2 groups: the cooperation of Chinese and Western medicine group (21 cases) and Western medicine control group (25 cases). All patients underwent MRI and X-ray exammanon before and after treatment. All patients' clinical symptoms. MRI and X-ray examination data were analyzed and compared before and after treatment. Results The cooperation of Chinese and Western medicine group had statistical difference with Western medicine group(P〈0.05) , effective rate of the former was 95%, while the latter was 72%. Post- therapy MRI showed that synovial thickness reduced, Synovial and pannus enhancement decreased, bone and cartilage erosion did not increased, marrow edema lessened or vanished, fluid accumulation in joint reduced. There were no obvious changes on X-ray examination before and after treatment. Conclusions The cooperation of Chinese and Western medicine treatment was better than western medicine alone. MRI could effectively assess RA treatment, so clinical promotion might be done.
分 类 号:R445.2[医药卫生—影像医学与核医学] R593.22[医药卫生—诊断学]
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