100kVp条件下碘克沙醇(270mgI/mL)应用于主动脉CTA检查的可行性研究  

Feasibility of aorta CT angiography using 100kVp technique and iodixanol(270mg I/mL)as contrast medium

作　　者：姜原[1] 赵永为[1] 王霄英[1] 张保翠[1] 王蕊[1] 罗健[1] 高福生[1] 何静[1] 

机构地区：[1]北京大学第一医院医学影像科,北京100034

出　　处：《放射学实践》2014年第4期357-360,共4页Radiologic Practice

摘　　要：目的:探讨100kVp条件下碘克沙醇(270mg I/mL)应用于主动脉CTA检查的可行性。方法:临床疑诊主动脉病变而行主动脉CTA检查的连续21例患者,分为两组,分别采用不同的CT扫描方案:A组10例,采用管电压120kVp,对比剂为碘帕醇(370mg I/mL);B组共11例,采用管电压100kVp,对比剂为碘克沙醇(270mg I/mL)。采用两独立样本t检验(非正态分布采用Mann-Whitney U检验)来比较两组的临床资料、CT辐射剂量、图像质量主、客观评价指标。结果:两组患者的性别、年龄和身体质量指数(BMI)的差异均无统计学意义(P=0.132、0.151和0.814)。两组的CT辐射剂量差异亦无统计学意义(P>0.05)。B组患者接受碘的剂量明显低于A组,且差异有高度统计学意义(P<0.001)。两组图像主观评分的差异无统计学意义(P=0.898)。图像的客观评分:两组的主动脉主干及其主要分支的CT值均>300HU,差异无统计学意义(P>0.05);A组CNR优于B组,2组差异有高度统计学意义(P=0.002)。结论:使用100kVp、碘克沙醇(270mg I/mL)进行主动脉CTA检查可以满足临床诊断需要。Objective：To evaluate the feasibility of using 100kVp as tube voltage and iodixanol （270mg I/mL） as contrast medium in aorta CT angiography （CTA）. Methods： 21 continuous patients with clinically suspected aortic lesion underwent aorta CT angiography. They were divided into two groups（Group A and B） based on different scan protocol. Group A included 10 patients using following parameters： 120kVp and iopamidol （370mg I/mL）. Group B included 11 patients using following parameters： 100kVp and iodixanol （270mg I/mL）. The clinical information,CT radiation dose,objective and subjective assessment of image quality of these two groups were retrospectively analyzed by independent t test or Mann- Whitney U test. Results：The differences of sex,age and body mass index （BMI） of two groups were not statistically signifi- cant （P = 0.132,0.151 and 0.814, respectively）. The difference of CT radiation dose of two groups was not statistically significant （P〉0.05）. The volume of iodine received in Group B was significantly lower than that of Group A,with significant statistic difference （P〈0. 001）. The difference of subjective assessment score of image quality in two groups was not statis- tically significant （P=0. 898）. The average CT values of the aorta trunk and its major branches in two groups were higher than 300HU,but there was no statistically difference between two groups （P〉0.05）. The CNR in Group A was better than that of Group B, with significant statistic difference （P= 0. 002）. Conclusion：High quality images of aorta CTA, which can meet the needs of clinical diagnostic,can be acquired by using 100kVp as tube voltage and iodixanol （270mg I/mL） as contrast medium.

关 键 词：主动脉 体层摄影术 X线计算机 血管成像 对比剂 辐射量 

分 类 号：R816.2[医药卫生—放射医学] R543.1[医药卫生—临床医学]