100kVp条件下碘克沙醇(270mgI/mL)应用于肾动脉CTA检查的可行性研究  

Feasibility of using 100kVp technique in renal artery CT angiography with iodixanol(270mg I/mL)

作　　者：雷平贵 赵永为[1] 王霄英[1] 王鹤[1] 张保翠[1] 杨学东[1] 高福生[1] 

机构地区：[1]北京大学第一医院医学影像科,北京100034

出　　处：《放射学实践》2014年第4期361-364,共4页Radiologic Practice

摘　　要：目的:探讨100kVp条件下、使用碘克沙醇(270mg I/mL)行肾动脉CTA检查的可行性。方法:18例行肾动脉CTA检查的连续病例根据CT扫描管电压分为两组:100kVp组(10例)和120kVp组(6例),记录2组的容积CT剂量指数(CTDIvol),计算体型特异性剂量估计(SSDE)值。由2位有经验的影像诊断医师对图像进行主观评分,包括:整体图像质量、图像细节(血管锐利程度、MPR显示分支、VR显示分支、MIP显示分支)。图像客观评价包括:目标血管和背景的CT值(腹主动脉动脉、双侧肾动脉、竖脊肌),对比噪声比(CNR)及信噪比(SNR)。两组间辐射剂量及客观评价指标的比较采用两独立样本t检验,主观评价指标的比较采用Mann-Whitney U检验。结果:100kVp组CTDIvol为(11.19±3.85)mGy,120kVp组为(17.37±2.63)mGy,两组间差异有统计学意义(P<0.05)。100kVp组SSDE为(15.48±4.41)mGy,120kVp组为(25.00±2.49)mGy,两组间差异有统计学意义(P<0.05)。主观评价:两组图像质量整体评分的差异无统计学意义(Z=-1.60,P>0.05);两组图像血管锐利程度评分的差异有统计学意义(Z=-2.162,P<0.05);两组中重组图像在显示血管分支方面,MPR(Z=-0.972,P>0.05)、VR(Z=-1.696,P>0.05)和MIP图像(Z=-1.626,P>0.05)间的差异均无统计学意义。客观评价:100kVp组腹主动脉CT值为(291±32)HU,120kVp组为(224±20)HU,两者差异有统计学意义(P<0.05);100kVp组肾动脉CT值为(278±37)HU,120kVp组为(222±15)HU,两者差异有统计学意义(P<0.05);空气CT值及标准差在100kVp组分别为(-992±2)和(9±2)HU,120kVp组分别为(-995±2)和(7±2)HU,两组间2个指标的差异均无统计学意义(P>0.05);两组图像的CNR分别为22±4及21±3,差异无统计学意义(P>0.05);两组图像的SNR分别为30±7及30±6,差异无统计学意义(P>0.05)。结论:100kVp条件下应用碘克沙醇(270mg I/mL)行肾动脉CTA检查,图像质量能满足诊断要求且降低了辐射剂量。Objective：To evaluate the feasibility of using 100kVp technique with iodixanol （270mg I/mL） in renal computed tomography angiography （CTA）. Methods： Sixteen Consecutive patients underwent renal artery CTA. They were divided into 100kVp group （10 patients） and 120kVp group （6 patients）. The radiation dose and size-specific dose estimation （SSDE） of these two groups were recorded. The image quality was evaluated subjectively with 5 scale method by two experienced radiologists,including image quality as a whole, detail image quality （sharpness of blood vessels, blood vessel branches displayed on MPR, VR and MIP）. The objective evaluation included attenuation of aimed blood vessels （abdominal aorta, bilateral renal arteries） and the attenuation of psoas major muscle at the same level as reference,and contrast-to-noise ratio （CNR）, signal-to-noise ratio （SNR） were calculated. The radiation dose and objective evaluation parameters were statically analyzed with t test,and the subjective evaluation parameters were analyzed with Mann-Whitney U test. Results： The CTDIvol in 100kVp group was （11. 19±3.85）mGy, in 120kVp group was （17.37±2.63）mGy,with significant statistic difference （P〈0.05）. The SSDE of 100kVp group was （15.48±4.41）mGy,in 120kVp group was （25.00±2.49）mGy, with significant statistic difference （P〈0.05）. There was no significant difference in the image quality as a whole in subjective evaluation between the 2 groups （Z=- 1.60, P〉0.05）. Significant difference was existed in the sharpness of blood vessels between the 2 groups （Z=-2. 162,P〈0.05） ;whereas no statistic difference was showed in the vessel branches displayed on MPR, VR and MIP （Z=- 0. 972, P〉0.05 ; Z= - 1. 696, P〉 0.05 ; Z=- 1. 626, P〉0.05）, respectively. For objective evaluation,the CT values of abdominal aorta and renal artery in 100kVp group and 120kVp group was [（291±32） vs （224±20） HU,P%0.05）] and [（278±37） vs （222 ± 15） HU, P%0

关 键 词：肾动脉 CT血管成像 对比剂 迭代重建 辐射量 体型特异性剂量估计 

分 类 号：R816.7[医药卫生—放射医学]