^18F-FDG正电子断层显像在分化型甲状腺癌中的应用进展  

Application Progress of ^(18)F-FDG Positron Emission Tomograph in Differentiated Thyroid Cancer

作　　者：黄蕤[1] 综述 匡安仁[1] 审校 

机构地区：[1]四川大学华西医院核医学科,成都610041

出　　处：《生物医学工程学杂志》2014年第2期445-451,共7页Journal of Biomedical Engineering

基　　金：国家自然科学基金面上项目资助(81071184);国家自然科学基金青年基金资助项目(30600153);卫生行业科研专项项目“甲状腺疾病的诊断及治疗”资助(201002002)

摘　　要：正电子断层显像(PET)从代谢角度诊断肿瘤,敏感性高,PET/CT同机图像融合提供的功能和解剖信息更有利于图像解释。18F-FDG是最常用的PET肿瘤显像剂,在分化型甲状腺癌(DTC)也得到很好的应用,特别是131I全身显像阴性而甲状腺球蛋白阳性患者复发和转移病灶的寻找。本文就18F-FDG PET显像在DTC患者术前分期、探寻复发和转移灶、制定治疗方案及预后研究方面的应用进行综述。Positron emission tomography （PET） is a highly sensitive and low invasive technology for cancer biological imaging. Integrated PET/computed tomography （PET/CT） cameras combine functional and anatomical information in a synergistic manner that improves diagnostic interpretation. The role of ^18F FDG PET/CT in differentiated thy- roid cancer （DTC） is well established, particularly in patients presenting with elevated thyroglobulin （Tg） levels and negative radioactive iodine scan. This review presents the evidence supporting the use of ^18F FDG PET/CT through- out the diagnosis and management of thyroid cancer, and provides suggestions for its clinical uses.

关 键 词：FDG 正电子断层显像 分化型甲状腺癌 

分 类 号：R817.4[医药卫生—影像医学与核医学]