持续腰大池引流治疗开颅术后颅内感染的疗效  

Effect of continuous lumbar cisterna drainage on intracranial infection after craniotomy

作　　者：杨地[1] 李华英[1] 吕文[1] 万勇[1] 陈成[1] 罗伟坚[1] 向进[1] 

机构地区：[1]暨南大学第二临床医学院深圳市人民医院神经外科,广东518020

出　　处：《齐齐哈尔医学院学报》2014年第6期810-811,共2页Journal of Qiqihar Medical University

摘　　要：目的探讨持续腰大池引流治疗开颅术后颅内感染的疗效。方法回顾性分析2009年5月至2013年5月我院收治的80例开颅术后颅内感染患者,根据治疗方案不同分为观察组和对照组,各40例。观察组给予持续腰大池引流配合抗生素治疗,对照组单独给予抗生素治疗。观察两组患者治疗有效率、体温与脑脊液变化。结果观察组治疗有效率为95.0%,对照组治疗有效率为92.5%,差异无显著性(P>0.05);治疗前,两组患者基础体温、脑脊液白细胞、蛋白、葡萄糖水平无明显差异(P>0.05),治疗后,观察组1 d、3 d基础体温、脑脊液白细胞计数等指标,均明显低于对照组,差异均有显著性(P<0.05),治疗后7 d,上述指标两组无明显差异(P>0.05)。结论持续腰大池引流治疗开颅术后颅内感染,可以早期控制体温、感染,治疗有效率较高,值得临床推广。Objective To investigate the effect of continuous lumbar cisterna drainage on intracranial infection after craniotomy. Methods 80 cases with intracranial infection after craniotomy in our hospital from May 2009 ~ May 2013 were retrospectively analyzed and according to the different treatment schemes,were divided into observation group and control group,40 cases in each. The observation group was given continuous lumbar cistern drainage combined with antibiotic therapy,while the control group was only given antibiotic treatment. The treatment efficiency,temperature and cerebrospinal fluid changes of patients in two groups were observed. Results The effective rate of observation group was 95%,and the effective rate of control group was 92. 5%, and there was no significant difference( P > 0. 05). Before treatment,there were no significant difference in the basal body temperature,leukocyte,protein,glucose levels in cerebrospinal fluid of the patients between two groups( P > 0. 05). After one day and 3days treatment,basal body temperature,cerebrospinal fluid leukocyte counts in the observation group,were significantly lower than those in the control group,and the differences were significant( P < 0. 05). After 7days treatment,those indexes between the two groups had no significant difference( P >0. 05). Conclusions Continuous lumbar cistern drainage in the treatment of intracranial infection after craniotomy,can early control temperature,and infection,with high cure rate,and is worthy of the clinical promotion.

关 键 词：持续腰大池引流 开颅 颅内感染 

分 类 号：R651.1[医药卫生—外科学]