骨外尤文肉瘤临床病理观察  

Clinical pathologic observation on Extraskeletal Ewing 's Sarcoma

作　　者：孙宇[1] 路瑶[2] 何苗[1] 范桂莲[1] 李慧峰[1] 

机构地区：[1]黑龙江省大庆油田总医院病理科,163001 [2]黑龙江省大庆油田总医院放射科,163001

出　　处：《齐齐哈尔医学院学报》2014年第7期965-967,共3页Journal of Qiqihar Medical University

摘　　要：目的探讨骨外尤文肉瘤的病理组织学及免疫组化特点,从而更好的对其进行治疗及估计预后。方法结合文献分析5例骨外尤文肉瘤的临床病理资料。结果其中4例为女性,1例为男性,中位年龄18岁,术后随访1例于20个月、1例于15个月生存良好,1例肺转移,2例失访。病理形态与其它幼稚细胞肿瘤相鉴别,免疫组化Vim、CD99均阳性,CgA、PAS部分呈+/-。骨外尤文肉瘤临床诊断困难,诊断主要依赖病理组织学及免疫组化。结论骨外尤文肉瘤恶性程度高,早期诊断困难,易误诊及漏诊,应结合病理资料进行个体化治疗及评估。Objective To explore histopathological and immunohistochemical characteristics of Extraskeletal Ewingg sarcoma, so as to better estimate its treatment and prognosis. Methods The medical charts of five patient with the diagnoses of Extraskeletal Ewing＇s Sarcoma were retrospectively reviewed. Results 4 cases of them were female, 1 was male, the median age was 18, 2 eases were followed up for 20 months, 15 months survival were good, 1 cases of lung metastasis, 2 cases missed. Pathological morphology and other naive cells should be differentiated. Vim（ ＋ ） ,CD99（ ＋ ） ,part of them CgA, PAS（ ＋/- ）. Clinical diagnoses was difficult and the diagnosis should mainly relied on the pathological and histological and immunohistochemical. Conclusions Malignant degree of Extraskeletal Ewing＇s sarcoma is high, early diagnosis is difficult, often misdiagnosed and missed, pathological data should be combined with individualized treatment and evaluation.

关 键 词：骨外尤文肉瘤 原始细胞肿瘤 

分 类 号：R581.3[医药卫生—内分泌]