脑细胞微环境研究的情报学分析  

Informational analysis of brain cell microenvironment

作　　者：李维[1] 韩鸿宾[2] 

机构地区：[1]100191北京大学医学图书馆 [2]北京大学第三医院北京市磁共振成像设备与技术重点实验室

出　　处：《中华医学科研管理杂志》2014年第2期219-223,232,共6页Chinese Journal of Medical Science Research Management

基　　金：国家自然基金（31271161）

摘　　要：脑细胞微环境,也称为脑组织通道,是由脑细胞外间隙及其内容物共同组成.长期以来,由于研究技术手段的限制,其在认知与脑病发生发展中的作用没有得到足够的重视.随着医学成像技术的成熟和发展,该领域的研究将可能为脑认知科学的发展开辟新研究空间,并为脑病诊治与新药研发提供新途径与新方向.本文以医学情报学方法揭示脑科学发展热点的特征及脑细胞微环境发展历史与延革,分析神经学建构的文献发展过程,为今后的研究者提供借鉴和思路.Brain cell microenvironment, also known as cerebral tissue channel, consists of the brain extraeellular space and its contents. For a long time, because of the limit of technology, the re- search about brain extracellular space hasnrt been given enough attention in the field of cognitive sci- ences and neuroscience. With the development of medical imaging technology, the research about brain extracellular space will open up a new space for brain and cognitive sciences, and provide a new ap proach for diagnosis and treatment of encephalopathy. Based on the method of medical informatics, this article reveals hot topics on brain science, presents the history of the research about brain cell microenvironment, and analyzes the construction of neurology literature so as to provide reference for the future researchers.

关 键 词：微环境 脑细胞外隙 脑组织通道 文献计量 信息挖掘 神经科学 

分 类 号：G353.1[文化科学—情报学]