抗系统性白念珠菌感染的先天性免疫  

Innate immunity response in Anti-systemic Candida albicans infection

作　　者：陈霞[1] 崔凡[2] 林昭春[2] 

机构地区：[1]泸州医学院,泸州646000 [2]四川省医学科学院&四川省人民医院皮肤病性病研究所,成都610031

出　　处：《中国真菌学杂志》2014年第1期52-55,59,共5页Chinese Journal of Mycology

摘　　要：白念珠菌是引起浅部、深部真菌感染常见的病原菌。先天免疫反应在宿主抗系统性白念珠菌感染中起主导作用。介导宿主抗念珠菌感染的先天性免疫包括一系列真菌识别受体及免疫效应细胞。宿主对系统性白念珠菌感染的免疫反应是决定患者预后的关键。本文就宿主抗系统性白念珠菌感染的先天性免疫机制进行综述。Candida albicans is a common pathogen which may induce superficial and deep infection of human.It is believed that innate immune response plays a leading role in the host anti-systemic infection of Candida albicans.Innate immune response mediating anti-Candida infection comprises a range of fungal recognition receptors and immune effector cells.Host immune response to systemic Candida albicans infection is critical for the prognosis of patients.In this paper,the mechanism of innate immune response in host anti-systemic Candida albicans infection was summarized.

关 键 词：白念珠菌 系统性感染 先天性免疫 

分 类 号：R379.4[医药卫生—病原生物学]