珍黄丸防治局部晚期鼻咽癌治疗中放射性口咽炎30例  

Clinical Study of Zhenhuang Pills used to Prevent and Control of Radioactive Oral Cavity Mucositis in Locally Advanced Nasopharyngeal Carcinoma Treatment

作　　者：徐新颜[1] 万彦婷[2] 洪燕[2] 

机构地区：[1]江西省萍乡市人民医院,萍乡337055 [2]武警江西总队医院门诊部,南昌330030

出　　处：《江西中医学院学报》2013年第6期12-14,共3页Journal of Jiangxi College of Traditional Chinese Medicine

摘　　要：目的:探讨珍黄丸用于减轻局部晚期鼻咽癌放化疗导致的放射性口腔粘膜炎及咽炎的疗效。方法 60例局部晚期鼻咽癌患者,同步放化疗,随机分成实验组(珍黄丸组0.4g口服3次/d),对照组(常规漱口液:利多卡因、地塞米松、庆大霉素各1支配在250mL生理盐水中)组,自放疗开始分别给予药物治疗,观察两组口腔粘膜炎及咽炎的发生情况和程度,总治疗时间和近期疗效。结果:实验组放射性口腔粘膜炎及咽炎的症状轻于对照组,有效率高于对照组,对照组出现2例因反应较重,导致治疗中断几天。近期疗效无显著性差异。结论:珍黄丸明显减轻局部晚期鼻咽癌患者的放射性口腔粘膜炎及咽炎,且无明显毒副作用,使用方便,易于接受,不影响疗效。objective ：To investigate the effect of Zhenhuang pils used to relieve locally advanced nasopharyngeal carcinoma of radioactive oral cavity mucositis caused by radiation and chemotherapy and the curative effect of pharyngitis. Method：Total of 60 patients withlocally advanced nasopharyngeal carcinoma, chemoradiation, randomly divided into experimental group （ Zhenhuang pilsl group 0.4 g orally 3 times/day） , the control group （routine mouthwash： lidocaine and dexamethasone, 1 command in 250 ml saline gentamycin） group, since radiotherapy were given drug therapy, observe two groups of the happening and degree of oral cavity mucositis and pharyn gitis, total treatment time and the recent curative effect. Results： The symptoms of radioactive oral cavity mucositis and pharyngitis lighter than the control group, the efficiency is higher than the control group, control group in 2 cases due to the reaction, cause the in terruption of treatment for a few days. The recent result there was no significant difference. Conclusion： Zhenhuang pilsl significantly reduce locally advanced nasopharyngeal carcinoma patients with radioactive oral mucositis and pharyngitis, and no obvious side effects, easy to use, easy to accept, but does not affect curative effect.

关 键 词：珍黄丸 局部晚期鼻咽癌 放射性咽炎 

分 类 号：R289.55[医药卫生—方剂学]