生物组织电导率图像的热声重建  

Reconstruction of Biological Tissue Conductivity Image by Thermoacoustic Imaging

作　　者：丁文正[1] 计钟[1] 娄存广[1] 

机构地区：[1]华南师范大学生物光子学研究院激光生命科学研究所,暨激光生命科学教育部重点实验室,广东广州510631

出　　处：《激光生物学报》2014年第1期41-44,共4页Acta Laser Biology Sinica

基　　金：科技部国家重点基础研究973计划项目(2011CB910402;2010CB732602);国家自然科学基金项目(81127004;11104087;61331001;11304103);广东省自然科学基金(S2013020012646;S2013040016419);高等学校博士学科点专项科研基金(20114407120001)资助

摘　　要：本文以微波热声效应为基础,报道了一种重建生物组织电导率相对分布图像的方法。和传统的微波热声像相比,重建得到的组织电导率图像消除了由于微波场能量密度分布不均匀带来的影响,能够准确的反映组织的介电特性差异,实现对肿瘤的早期发现。本文首先从理论上详细推导了获得生物组织电导率分布图像的原理,然后在实验中通过结合已有的脉冲微波成像系统,重建得到了一块肌肉组织的电导率分布图像。实验结果表明利用热声成像技术,组织的电导率分布图像能够被清晰的重建,本研究为推进热声成像技术的实用性打下了理论和实验基础。Based on the thermoacoustic effect,we report a new method to reconstruct the conductivity image of the bio-logical tissue.Compared with the traditional thermoacoustic images,the influence brought by the uneven distribution of microwave field is eliminated in the tissue conductivity image.It can accurately reflect the dielectric differences of bio-logical tissue,and realize the early detection of cancer.The theory deduced the principle of reconstructing the conductiv-ity image of the biological tissue.Finally,with the existing thermoacoustic imaging system,we reconstructed the conduc-tivity distribution image of muscle tissue in the experiment.Our experimental results indicated that the conductivity dis-tribution image can be clearly reconstructed by thermoacoustic imaging technology.This study laid a theoretical and ex-perimental basis for the practicality study of thermoacoustic technology.

关 键 词：热声成像 脉冲微波 电导率 相对分布 

分 类 号：Q684[生物学—生物物理学] R312[医药卫生—基础医学]