影响种植支架材料生物相容性的因素  

Facts affecting biocompatibility of implant scaffold

作　　者：赵惠[1] 李潇[2] 金柱坤[2] 杨凯[2] 

机构地区：[1]南方医科大学口腔医学院,广州510515 [2]广州军区总医院口腔科,广州510010

出　　处：《国际口腔医学杂志》2014年第3期341-346,共6页International Journal of Stomatology

基　　金：全军医学科研"十二五"面上课题(CWS11J271);广东省产学研结合项目(2012B091100171)

摘　　要：支架材料是骨组织工程中的关键要素,材料的生物相容性与支架的宏观结构和微观结构直接相关。改变支架的结构将直接影响到材料的综合性能,支架材料的表面粗糙度、表面能、孔径、内连接径、孔隙率、血管化、表面改性及材料复合、纳米技术等,皆会影响种子细胞在支架材料上的黏附、增殖和分化,本文就以上研究进展作一综述。Scaffolds are a key element of bone tissue engineering technology. The macro-structure and micro-structure are directly related to the biocompatibility of scaffolds. Changes in the structure directly affect the overall performance of scaffolds. This paper reviews the scaffold surface roughness, surface energy, aperture, connection diameter, porosity, vascularization, surface modification and composite materials, nanotechnology, and the structural changes affecting seed cell adhesion, proliferation, and differentiation on the scaffold.

关 键 词：生物相容性 种植 支架 

分 类 号：R318.08[医药卫生—生物医学工程]