糖尿病肢体动脉闭塞症中医证型与股总动脉内—中膜厚度的相关性研究  

Correlative Study between Differentiated Syndrome of Chinese Medicine and Intima-Medial Thickness of Common Femoral Artery in Diabetic Arterial Occlusion of Lower Extremities

作　　者：陈柏楠[1] 李彦州[2] 许永楷[1] 宋福晨[1] 赵波[1] 

机构地区：[1]山东中医药大学附属医院,山东济南250014 [2]洛阳市中心医院,河南洛阳471000

出　　处：《世界中西医结合杂志》2014年第4期386-388,共3页World Journal of Integrated Traditional and Western Medicine

基　　金：山东省中医药科技发展计划重点项目(No.2009Z004-2)

摘　　要：目的探讨股总动脉内—中膜厚度等检测指标与糖尿病肢体动脉闭塞症(DAO)中医证型的相关性。方法把DAO患者分为血瘀证和湿热证两型,选取股总动脉内—中膜厚度(IMT)、股总动脉管腔内径、股总动脉管腔狭窄度、空腹血糖(FBG)、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)、内皮素-1(ET-1)、一氧化氮(NO)、血小板(PLT)、纤维蛋白原(Fg)等12项实验室相关指标及彩超检查情况,采用Logistic回归分析的方法初步探讨其与中医证型的相关性。结果筛选出对DAO中医证型贡献度大的优化指标,即IMT、Fg、TC、HDL,建立了最优回归预测方程。结论 IMT、Fg、TC、HDL可作为评定DAO中医证型的微观辨证参考指标。Objective To discuss the correlation between the determined indexes of intima - medial thickness of common femoral artery（ FA - IMT） and the differentiated syndrome of Chinese medicine in dia- betic arterial occlusion of lower extremities （DAO）. Methods DAO patients were divided into blood stasis type and damp heat type. Twelve laboratory relevant indexes such as IMT, lumen inner diameter（ LID）, lumen stenosis degree （ LSD）, FBG, TC, TG, LDL, HDL, ET - 1, NO, PLT and Fg and color ultrasonic examination were collected. Logistic regression analysis was used to explore preliminarily the correlation between those in- dexes and the differentiated syndromes of Chinese medicine. Results The optimizing indexes including IMT, Fg,TC and HDL were screened, with the high contribution degree to the differentiated syndromes of Chi- nese medicine in DAO. The optimal regression prediction equation was set up. Conclusion IMT, Fg, TC and HDL can be the reference indexes for the evaluation of the microcosmic syndrome differentiation of DAO in Chinese medicine.

关 键 词：糖尿病肢体动脉闭塞症 中医证型 内-中膜厚度 

分 类 号：R587.2[医药卫生—内分泌]