刺激家兔面神经核腹内侧区对颏舌肌肌电活动的抑制效应  

Inhibitory effects on the myoelectric activities of genioglossus during stimulating ventral medial area of nucleus facialis in rabbits

作　　者：王丽[1] 徐欣[2] 刘磊[1] 

机构地区：[1]山东医科大学基础医学院生理学教研室 [2]卫生部耳鼻喉科学重点实验室中国睡眠呼吸障碍研究中心,济南250012

出　　处：《基础医学与临床》2001年第1期81-84,共4页Basic and Clinical Medicine

基　　金：山东省科学技术委员会基金资助项目!(No .99B1CAA1)

摘　　要：本研究在 2 6只氨基甲酸乙酯麻醉、断双侧迷走神经的健康成年家兔上观察了电、化学刺激面神经核腹内侧区 (vMNF)对颏舌肌肌电活动的影响。结果如下 :(1)长串电脉冲刺激vMNF导致颏舌肌肌电活动明显被抑制 ;(2 )在vMNF内微量注射谷氨酸钠 ,颏舌肌肌电活动出现明显的抑制效应 ;(3)单脉冲电刺激vMNF引起颏舌肌抑制反应的潜伏期为 (2 0 6± 0 4)ms。结果表明 :vMNF的兴奋能降低颏舌肌的肌电活动 ,从而提示其具有增强上呼吸道阻力的作用。The effects of electrical and chemical stimulation of the vertral medial area of nucleus facialis (vMNF) on the myoelectric activities of genioglossus were observed in 26 urethane anaesthetized and vagotomized rabbits. The results are as follows: (1) Long train electrical stimulation at the vMNF inhibitited the myoelectric activities of genioglossus markedly. (2) Microinjection of glutamate into the vMNF caused inhibitory response of the myoelectric activities of genioglossus. (3) When single pulse electrical stimulation on vMNF, measurement latency of genioglossus myoelectric activities was (20 6±0 4)ms. These results suggested that the excitation of vMNF could decrease the myoelectric activities of genioglossus so that the resistance of upper airway might be enhanced.

关 键 词：面神经核腹内侧区 颏舌肌 刺激 上呼吸道阻力 肌电活动 家兔 

分 类 号：R766[医药卫生—耳鼻咽喉科]