益肾化瘀法对Ⅱ型糖尿病血液流变学、SOD、LPO水平及血管病变的影响  

Effect of Method of Reinforcing Kidney and Removing Blood Stasis on Blood Rheology, Levels of SOD and LPO and Blood Vessel Pathological Changes in Type II Diabetes Patients

作　　者：王旭[1] 陈金锭[1] 

机构地区：[1]南京中医药大学第一临床医学院,江苏南京210029

出　　处：《南京中医药大学学报》2001年第1期20-22,共3页Journal of Nanjing University of Traditional Chinese Medicine

基　　金：江苏省科委自然科学基金!(BS96 0 5 0 )

摘　　要：目的　观察益肾化瘀法治疗Ⅱ型糖尿病对血液流变学、SOD、LPO水平的影响 ,并探讨其与血管病变关系。方法　Ⅱ型糖尿病符合肾虚血瘀证者 6 5例 ,分为血管病变组和无血管病变组 ,分别观察治疗前后FBG、PBG、ηb、ηP、IR、SOD、LPO变化。结果　 2组治疗前血糖、血液流变学、SOD、LPO值具有差异 ,P <0 .0 5～ 0 .0 1。治疗后FBG、PBG、ηb、ηP、IR、SOD、LPO 2组均有改善 ,血液流变学以血管病变组改善明显。血管病组FBG与 ηb、ηp、IR、LPO呈明显正相关 (P <0 .0 5～ 0 .0 1) ,与SOP呈负相关 (P <0 .0 5 )。。结论　益肾化瘀法对Ⅱ型糖尿病及其血管病变具有有效的防治作用。OBJECTIVE To observe the effect of the method of reinforcing the kidney and removing blood stasis on blood rheology, the levels of SOD and LPO and blood vessel pathological changes. METHOD The changes in FBG, PBG,ηb,ηP, IR, SOD and LPO of patients with deficiency of the kidney and blood stasis were observed before and after the treatment. RESULT Great differences were observed between the two groups ( P <0.05～0.01). CONCLUSION The method of reinforcing the kidney and removing blood stasis can effectively prevent NIDDM and its blood vessel pathological changes.

关 键 词：Ⅱ型糖尿病 益肾化瘀法 血液流变学 SOD LPO 血管病变 中医药疗法 

分 类 号：R259.871[医药卫生—中西医结合] R255.405[医药卫生—中医内科学]