动态监测血清β-HCG、孕酮和雌二醇在预测早期先兆流产预后的临床意义  

Clinical significance of dynamic monitoring serum beta HCG、progesterone and estradiol in prediction of prognosis of early threatened abortion

作　　者：赖有行[1] 叶青[1] 黄瑞玉[1] 周才[1] 周晓莹[1] 李志云[1] 

机构地区：[1]广东省妇幼保健院检验科,广东广州510010

出　　处：《中国优生与遗传杂志》2014年第3期83-84,共2页Chinese Journal of Birth Health & Heredity

摘　　要：目的探讨动态监测血清人绒毛膜促性腺激素β亚单位（β-HCG）、孕酮（P）与雌二醇（E2）在早期先兆流产预后中的临床价值。方法选择197例孕6~8周的单胎孕妇,均抽取静脉血动态监测血清β-HCG、P、E2水平。同时追踪妊娠结局将所有孕妇分为3组,妊娠失败组58例,继续妊娠组74例,正常妊娠组65例。结果第6~8周妊娠失败组血清β-HCG、P、E2水平均明显低于正常妊娠组和继续妊娠组,差异有统计学意义（P〈0.01）。结论联合动态监测血清β-HCG、P与E2水平,对于预测先兆流产患者妊娠结局有一定的指导意义。Objective： To investigate the dynamic monitoring of serum human chorionic gonadotrophin beta subunits（ beta HCG） and progesterone（ P） and estradiol（ E 2） in the clinical value of early prognosis of threatened abortion. Methods： Choose 197 cases of single pregnant women at 6 ~ 8 weeks,both extraction of venous blood dynamic monitoring beta HCG,P,serum E 2 levels. At the same time tracking the pregnancy outcome,all pregnant women can be divided into 3 groups,group of 58 cases of pregnancy failure, pregnancy group 74 examples,group of 65 cases of normal pregnancy. Results： 6 ~ 8 weeks of pregnancy failure group of beta HCG, P,serum E 2 levels were significantly lower than normal pregnancy and pregnancy group,the difference was statistically significant（ P 0. 01）. Conclusion： The combined dynamic monitoring serum beta HCG,P and E 2 levels,in predicting pregnancy outcome threatened abortion patients have certain guiding significance.

关 键 词：先兆流产 绒毛膜促性腺激素β-HCG 孕酮 雌二醇 

分 类 号：R714.21[医药卫生—妇产科学]