应用速度向量成像技术评价T2DM患者颈动脉斑块长轴力学特征  

Evaluation of mechanical characteristics of longitudinal section on carotid plaques in T2DM using velocity vector imaging

作　　者：董叶[1] 林红军[1] 

机构地区：[1]南京医科大学第一附属医院超声科,江苏南京210029

出　　处：《南京医科大学学报（自然科学版）》2014年第2期234-238,共5页Journal of Nanjing Medical University(Natural Sciences)

基　　金：卫生部科研基金(LW201001)

摘　　要：目的:应用速度向量成像技术(velocity vector imaging,VVI)评价T2DM患者颈动脉斑块长轴力学特征,比较其与正常人颈动脉斑块在长轴方向上速度、应变及应变率的差异。方法:将100例受试者按血糖水平均分为糖尿病组和对照组,使用Acuson Sequoia C2000超声探测仪采集颈动脉图像资料。应用VVI技术检测颈动脉斑块表面5个感兴趣区的运动信息,获得5个感兴趣区速度、应变及应变率的正向峰值、负向峰值和峰值差值。结果:糖尿病组速度、应变、应变率等相应的力学指标都较正常组减小;糖尿病组和正常组组内斑块各个感兴趣区速度均是先减小再增大;糖尿病组内应变及应变率均是近心端肩部大于其余各点。结论:VVI技术可以很好的评价2型糖尿病患者颈动脉斑块长轴上力学特征。Objective：To evaluate the mechanical properties of longitudinal section of carotid plaque in patients with T2DM,and compare the indexes of velocity,strain and strain rate with normal controls. Methods：One hundred subjects were divided equally into diabetic group and control group according to blood glucose level. Acuson Sequoia C2000（Siemens） was used to collect the image data of carotid plaque. Velocity vector imaging technique was performed to detect the motion information of 5 regions of interest on the surface of carotid plaque,and obtain the positive peak,negative peak and peak difference of velocity,strain and strain rate. Results：All indexes of the diabetic group were smaller than the control group. In the two groups,the indexes of velocity were firstly decreased and then increased. And in the diabetic group,the proximal end of shoulder was greater than the remaining points for strain and strain rate. Conclusion： Velocity vector imaging is an effective technique for evaluating the mechanical properties of carotid plaque in patients with T2DM.

关 键 词：速度向量成像技术 2型糖尿病 动脉粥样硬化 斑块 应变 

分 类 号：R445.1[医药卫生—影像医学与核医学]