应用Logistic回归分析鼻内镜下治疗慢性鼻-鼻窦炎效果影响因素  

Logistic regression analysis of factors influencing curative effect of endoscopic sinusitis surgery for chronic rhinosinusitis

作　　者：皮文[1] 吕凌云[1] 王成禹[1] 

机构地区：[1]淮安市第一人民医院耳鼻咽喉科,江苏淮安223300

出　　处：《中国耳鼻咽喉颅底外科杂志》2014年第1期17-20,共4页Chinese Journal of Otorhinolaryngology-skull Base Surgery

摘　　要：目的探讨鼻内镜下手术治疗慢性鼻-鼻窦炎患者的临床治疗效果及影响因素。方法选择我院2010年1月-2011年12月行鼻内镜手术的慢性鼻-鼻窦炎患者270例，其中不伴有鼻息肉慢性鼻-鼻窦炎患者146例，伴鼻息肉者124例。收集相关临床资料，对鼻内镜术后6个月进行疗效评定，并应用Logistic回归分析影响手术治疗效果的危险因素。结果鼻内镜下手术治疗270例慢性鼻-鼻窦炎患者，总体病情完全控制率达87．78％（237／270）；不伴鼻息肉组病情完全控制率达92．47％（135／146）明显高于伴鼻息肉组82．26％（102／124）（X^2=6．512，P=0．011），不伴鼻息肉组手术疗效明显优于伴鼻息肉组（X^2=7．539，P=0．023）；Logistic回归分析显示临床类型、是否伴有变应性鼻炎、VAS评分、Lund-Mackay评分、Lund—Kennedy评分、是否复发、术后随访依从性是影响手术疗效的主要因素。结论Logistic回归分析显示鼻内镜下治疗慢性鼻一鼻窦炎疗效除与是否伴有鼻息肉有关外，还与其他多种因素相关。Objective To investigate clinical effect and influence factors of endoscopic sinusitis surgery （ESS） for chronic rhinosinusitis （CRS）. Methods Clinical data of 270 patients with CRS treated by ESS from Jan. 2010 to Dec. 2011 were analyzed retrospectively. The clinical effect was evaluated 6 months after operation according to the evaluation standard for ESS and logistic regression analysis was performed to analyze the risk factors. Results The postoperative follow-up results showed a total disease control rate of 87.78% （237/270）. The disease control rate of CRS patients without nasal polyps was 92.47% （135/146） , which was significantly higher than that of the CRS patients with nasal polyps （ 82.26% , 102/124） （X2 = 6.512, P = 0.011 ） , The curative effect of CRS patients without nasal polyps was significantly better than that of ones with nasal polyps （X2 = 7. 539, P = 0. 023 ）. Logistic regression analysis showed that clinical classification, allergic rhinitis, visual analogue scale score, Lund- Mackay score, Lund-Kennedy score, recurrence and postoperative follow-up compliance were the major risk factors for ESS. Conclusions Logistic regression analysis showed the clinical effect and influence factors of endoscopic sinusitis surgery （ESS） for chronic rhinosinusitis （CRS） was accompanied by nasal polyps, and also related to other factors.

关 键 词：鼻窦炎 鼻内镜手术 因素分析 LOGISTIC回归 

分 类 号：O21[理学—概率论与数理统计] R765.9[理学—数学]