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作 者:赵远[1] 孙娜[1] 刘蓬蓬[1] 徐珊[1] 张凡[1,2] 贾天柱[1,2]
机构地区:[1]辽宁中医药大学,辽宁大连116600 [2]辽宁省中药炮制工程技术研究中心,辽宁大连116600
出 处:《中医药导报》2014年第4期12-15,共4页Guiding Journal of Traditional Chinese Medicine and Pharmacy
基 金:国家中医药管理局行业专项课题(19种生熟异用中药饮片临床规范使用研究;编号:201107007)
摘 要:目的:比较生晒参、红参与平性参对气虚大鼠的作用。方法:通过游泳劳损法结合限食法实验复制大鼠气虚证模型,分别给予生晒参、红参与平性参混悬液灌胃,比较三者对气虚大鼠的作用。结果:生晒参、红参与平性参能够增加大鼠耐疲劳游泳时间,降低cAMP的含量和cAMP/cGMP比值,并且升高cGMP的含量;同时能够降低LDH的活性。结论:生晒参、红参与平性参对气虚大鼠均有治疗作用,人参各高剂量组差异无统计学意义,在数值上显示生晒参与平性参优于红参。Objective: To compare the effect of sun-dried ginseng, red ginseng and mild property ginseng on Qi deficien- cy of rats. Methods: Swimming strain method and Caloric restriction method were applied to copy Qi deficiency syndrome model of rats, which were given sundried ginseng, red ginseng and mild property ginseng suspension garage respectively; the effect on qi deficiency rats was compared. Results: Sun-dried ginseng, red ginseng and mild property ginseng can increase rats fatigue endurance swimming, reduce the content of cAMP and cAMP/cGMP ratio, elevate the content of cGMP, as well as reduce the activity of LDH. Conclusions: Sun-dried ginseng, red ginseng and mild property ginseng and provide therapeutic effect of qi deficiency rats, without significant difference between the high dose group, un-dried ginseng, mild property ginseng are better than red ginseng, just in values.
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