儿感康口服液祛痰、止咳和平喘药学作用研究  

Pharmacodynamic Studies on Phlegm-Dispelling,Cough-Settling,Panting-Calming Action of Er-gan-kang-oral Liquid

作　　者：尹玲桃[1] 王宇红[1,2] 莫韦皓[3] 邓东方[3] 李心亮[1] 

机构地区：[1]湖南中医药大学药学院,湖南长沙410208 [2]湖南省中药粉体与创新药物省部共建国家重点实验室培育基地,湖南长沙410208 [3]湖南中医药大学第一附属医院,湖南长沙410007

出　　处：《中医药导报》2014年第5期95-97,共3页Guiding Journal of Traditional Chinese Medicine and Pharmacy

摘　　要：目的:研究儿感康口服液的祛痰、止咳、平喘作用。方法:采用小鼠酚红祛痰实验观察其祛痰作用;采用小鼠氨水引咳实验观察其止咳作用;采用乙酰胆碱联合组胺所致豚鼠哮喘实验观察其平喘作用。结果:儿感康口服液能显著增加大鼠痰量的排出,延长由氨水引起的咳嗽时间和由乙酰胆碱联合组胺诱导的引喘潜伏期。结论:感康口服液有显著的祛痰、止咳、平喘作用。Objective： To study the cough-settling, phlegm-dispelling and panting-calming actions of Er-gan-kang-oral liquid. Methods： The phlegm-dispelling effects were observed on Phenol red expectorant experiment; The panting-calming ef- fects were observed on ammonia water-induced cough model of mice; The panting-calming effects was observed by prolong the latent period of asthma induced by histamine and acetylcholine mixture in guinea pig. Results： Er-gan-kang-oral liquid could significantly increase the amount of rat sputum discharge, decrease the frequency of cough caused by ammonia water in mice and prolong the latent period of asthma induced by histamine and acetylcholine mixture in guinea pigs. Conclusion： Er-gan- kang-oral liquid has the phlegm-dispelling cough-settling and panting-calming actions.

关 键 词：儿感康口服液 祛痰 止咳 平喘 

分 类 号：R285.5[医药卫生—中药学]