卫气与变应性鼻炎黏膜免疫机制的相关性探讨  

Correlation between defensive qi and allergic rhinitis mucosal immune mechanism

作　　者：刘洋[1] 李昕蓉[1] 陈晴[1] 张勤修[2] 

机构地区：[1]成都中医药大学第一临床学院,成都610072 [2]成都中医药大学附属医院耳鼻咽喉科,成都610072

出　　处：《中华中医药杂志》2014年第5期1530-1533,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家自然科学基金面上项目(No.81273985);高等学校博士点学科专项科研基金项目(No.20125132110011);四川省国际科技合作与交流研究计划项目(No.2013HH0021)~~

摘　　要：近十余年来鼻腔黏膜免疫已经成为变应性鼻炎研究中的热点,而黏膜免疫系统理论与中医理论中的"卫气学说"具有较强的相关性。文章以卫气的"屏障""防御"以及"监督"作用为切入点,从黏膜免疫系统(MIS)的非特异性免疫、特异性免疫以及黏膜免疫与系统免疫的连接等多个层面对其相关性进行分析,并探讨其在变应性鼻炎发病机制中的作用机制,为变应性鼻炎的防治提供参考。In the past ten years, nasal mucosal immunity system （MIS） had become a hot spot in the study of allergic rhinitis and immunology. With the further research, the Chinese traditional medical scientist found that the theory of mucosal immune system and the theory of defensive ＇qi＇（Wei qi） in traditional Chinese medicine had closely correlation and through the study on its correlation to better explain the mechanism of allergic rhinitis. In this paper, from the perspective of the functions that ＇barrier＇ ＇defense＇ and ＇supervision＇ of defensive ＇qi＇ as the breakthrough points, to analyze its relevance with the functions of mucosal immune system （MIS） from three aspects： 1. the structure of the correlation between ＇barrier＇ of defensive ＇qi＇ and nonspecific immunity of MIS; 2. the function of the correlation between ＇defense role＇ of defensive ＇qi＇ specificity immunity of MIS; 3. the regulatory mechanism of the correlation between ＇supervision＇ of defensive ＇qi＇ and the whole and local connection in human immunity. And on this basis, the related pathogenesis of allergic rhihitis were explored and some further references for a better prevention and control of allergic rhinitis might be provided.

关 键 词：变应性鼻炎 卫气 黏膜免疫系统 相关性探讨 

分 类 号：R765.21[医药卫生—耳鼻咽喉科]