机构地区:[1]复旦大学附属儿科医院新生儿科,上海201102 [2]复旦大学附属儿科医院卫生部新生儿疾病重点实验室,上海201102 [3]上海市科委出生缺陷防治重点实验室,上海201102 [4]复旦大学附属妇产科医院新生儿科,上海200011
出 处:《中国循证儿科杂志》2014年第1期16-22,共7页Chinese Journal of Evidence Based Pediatrics
基 金:上海市科委重大课题:11DZ1950302;上海市卫计委重要疾病联合攻关项目:沪卫计科教2013-018
摘 要:目的在单中心汉族人口中建立正常足月新生儿18个体表信息的参考范围值。方法依据《人体测量手册》上提供的方法,选取复旦大学附属妇产科医院37~40周生后2 h内的595名健康足月、汉族和单胎新生儿,行身长、体重、头围、乳距、胸围、内眦间距、外眦间距、睑裂长、耳长、耳宽、鼻长、鼻宽、鼻高、口宽、人中线长、手长、手中指长和足长信息的直接测量,每个体表信息连续重复测量3次,取3次测量的平均值行统计学分析。应用LMS软件(light version)来构建分性别按照孕周的各测量的光滑的百分位数曲线。结果 2011年8月至2012年9月间符合本文纳入和排除标准的新生儿595例进入分析,男性305例,女性290例,其中37周83例(男40例,女43例),38周218例(男118例,女100例),39周185例(男91例,女94例),40周109例(男54例,女55例)。构建18个体表信息第3~97百分位数。37周新生儿中5/18个(27.8%)体表信息值男性>女性,P均<0.05,分别为耳长、耳宽、鼻宽、鼻长和足长;38周新生儿中11/18个(61.1%)体表信息值男性>女性,P均<0.05,分别为身长、体重、耳长、耳宽、鼻高、鼻宽、鼻长、口宽、手长、中指长和足长;39周新生儿中14/18个(77.8%)体表信息值男性>女性,P均<0.05,分别为身长、体重、头围、胸围、内眦间距、外眦间距、睑裂长、耳长、耳宽、鼻宽、鼻长、人中线长、手长和足长;40周新生儿中11/18个(61.1%)体表信息值男性>女性,P均<0.05,分别为身长、体重、头围、胸围、内眦间距、外眦间距、耳长、耳宽、鼻宽、足长和乳距,其余体表信息值性别差异均无统计学意义,P均>0.05。结论建立了单中心汉族足月新生儿18个体表信息的参考范围值和百分位数。男女新生儿5~14个体表信息值有差异,男性体表信息值>女性。Objective To provide reference values of 18 anthropometric parameters for term and healthy Han Chinese newborns in a single centre. Methods Healthy newborns were measured within two hours after birth using the method described by Hall's ' Handbook of Physical Measurements'. A total of 595 healthy singleton,born at the Obstetrical and Gynecological Hospital of Fudan University were included. Gestational weeks ranged from 37-40 weeks. Crown-heel length,weight,head circumference,chest circumference,internipple distance,inner canthal distance,outer canthal distance,palpebral fissure length,ear length,ear width, nasal length,nasal width,nasal depth,mouth width,philtrum length,hand length,middle finger length and foot length were measured directly. All the parameters were measured three times and the results were recorded. LMS software light version was used to construct the smoothed centile curves of parameters by gestational weeks and sex. Results A total of 595( 305 males,290 females) normal Han term singletons born at the Obstetrical and Gynecological Hospital of Fudan University from August 2011 to September 2012 were enrolled in the study,including 83 newborns born at 37 weeks( 40 males,43 females),218 born at 38 weeks( 118 males,100 females),185 born at 39 weeks( 91 males,94 females) and 109 born at 40 weeks( 54 males,55 females). The 3rd,5th,10th,25th,50th,75th,95th and 97th centile curves of 18 anthropometric parameters were constructed,cutoffs by gestational ages were provided by sex. Five parameters( 5 /18,27. 8%),including ear length,ear width,nasal width,nasal length and foot length,showed larger values( P < 0. 05) in males than females at 37 weeks. Eleven parameters( 11 /18,61. 1%),including crown-heel length,weight,ear length,ear width,nasal depth,nasal width,nasal length,mouth width,hand length,middle finger length and foot length,showed larger values( P < 0. 05) in males than female at 38 weeks. Fourteen parameters( 14/18,77. 8%),including crown-heel length,weight,head circumference,chest circumference
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