血管内支架置入术解除颈动脉狭窄对认知功能影响的对照研究  

Control study of endovascular stenting in relieving effect of carotid artery stenosis on cognitive function

作　　者：陈克强[1] 刁士元[1] 孙巧松[1] 刘华钊[1] 

机构地区：[1]广东省江门市中心医院神经内科,广东江门529030

出　　处：《中国医药科学》2014年第5期178-180,共3页China Medicine And Pharmacy

摘　　要：目的研究血管内支架置入术解除颈动脉狭窄对患者认知功能的影响。方法选择2012年1月～2013年3月江门市中心医院神经内科一区收治的颈动脉狭窄患者共36例作为临床研究对象，根据患者的意愿纳入手术组和对照组。其中手术组患者20例，使用血管内支架置入手术，对照组患者16例，使用常规药物治疗。分别在入院时和入院后3、6个月采用蒙特利尔认知估量表（MoCA）、简易精神评估量表（MMSE）评价患者的认知功能。结果手术组患者在入院后3个月和6个月的MoCA、MMSE评分均优于对照组患者，差异有统计学意义。结论与单纯药物治疗比较，颈动脉支架植入术能更有效改善颈动脉狭窄患者的认知功能障碍。Objective To study the role of endovaseular stenting in relieving the effect of carotid artery stenosis on cognitive function. Methods A total of 36 patients with carotid artery stenosis admitted to Department of Neurology of Jiangmen Central Hospital from January 2012 to March 2013 were selected as the clinical study subjects and divided into the surgical group and the control group according to the patients＇ willingness. The 20 patients of the surgical group received endovascular stenting and the 16 patients of the control group received conventional drug therapy. The Montreal Cognitive Assessment scale （MoCA） and Mini-Mental State Eximation scale （MMSE） were used to evaluate the patients＇ cognitive function at admission and 3 and 6 months after admission. Results The surgical group was better than the control group in MoCA and MMSE scores 3 and 6 months after admission, with statistical significant differences. Conclusion Compared to single drug therapy, endovascular stenting can improve the cognitive function impairment of carotid artery stenosis patients more effectively.

关 键 词：颈动脉狭窄 认知功能 血管内支架置入 

分 类 号：R543.4[医药卫生—心血管疾病]