Safety and efficacy of intravenous esmolol before prospective electrocardio- gram-triggered high-pitch spiral acquisition for computed tomography coro- nary angiography  

作　　者：Jin-Da WANG Hua-Wei ZHANG Qian XIN Jun-Jie YANG Zhi-Jun SUN Hong-Bin LIU LianCHEN Luo-Shan DU Yun-Dai CHEN 

机构地区：[1]Department of Cardiology, Chinese PLA General Hospital, 28 Fuxing Road, Beijing 100853, China

出　　处：《Journal of Geriatric Cardiology》2014年第1期39-43,共5页老年心脏病学杂志（英文版）

摘　　要：Background In order to acquire a high quality image with a low radiation dose, prospective electrocardiogram （ECG）-triggered computed tomography coronary angiography （CTCA） requires a stable heart rate （HR） 〈 65 beats/min. Esmolol has the advantage of reduc-ing HR. The objective of this article is to assess the value of intravenous esmolol treatment before prospective ECG-tr/ggered high-pitch spiral acquisition for CTCA. Methods From March 2013 to June 2013, 313 patients underwent prospective ECG-triggered CTCA. Two hundred and thirty two of them received esmolol before angiography. We retrospectively analyzed clinical characteristics, esmolol dose, radiation exposure dose, and the change in HR and blood pressure in these 232 patients. Results A total of 232 patients with a HR 〉 65 beats/rain before CTCA examination received intravenous esmolol treatment （mean dose of 57.26±15.39 rag）, The mean initial HR （HR1）, slowest HR （HR2）, and the HR 30 min after HR2 （HR3） were 75.06± 5.59, 60.75 ±4.00, and 75.54 ± 5.96 beats/min, respectively （HR1 vs. HR2, P 〈 0.0001; HRI vs. HR3, P = 0.377）. The mean time from esmolol administration to HR2 was 24.25 ± 4.97 s and the mean effective radiation dose was 2.28 ± 0.02 mSv. Conclusions HR could be rapidly controlled at an optimum level with intravenous esmolol before prospective ECG-triggered high-pitch spiral acquisition for CTCA. Consequently, the patients received a very low radiation dose.

关 键 词：ESMOLOL ELECTROCARDIOGRAM Coronary angiography Heart rate 

分 类 号：TP391.41[自动化与计算机技术—计算机应用技术] TQ463.4[自动化与计算机技术—计算机科学与技术]