Thinking on Functional Mechanism of Acupuncture for Inflammatory Bowel Diseases Based on Metabolomics  

作　　者：Dou Chuan-zi Feng Hui Zheng Xiao Liu Xiao-xu Zhu Xi-fa Liu Shi-min Wu Lu-yi Yang Ling Lu Yuan Zhang Wei-wei Liu Hui-rong Huang Guo-qi 

机构地区：[1]Shanghai Research Institute of Acupuncture and Meridian [2]Shanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine [3]Taizhou Hospital of Traditional Chinese Medicine, Zhejiang Province [4]Shanghai University of Traditional Chinese Medicine

出　　处：《Journal of Acupuncture and Tuina Science》2014年第2期73-79,共7页针灸推拿医学（英文版）

基　　金：supported by National Natural Science Foundation of China(No.81303033);Outstanding Academic Leaders Training Plan of Shanghai Health Care System(No.XBR2013106);National Basic Research Program of China(973 Program,No.2009CB522900);Natural Science Foundation of Shanghai(No.11ZR1434300)

摘　　要：Acupuncture has a good therapeutic effect in treatment of inflammatory bowel diseases(IBD), but its functional mechanism has not been systematically explained. Metabolomics is the scientific study of dynamic chemical processes involving metabolites as well as metabolic response of living organisms. Metabolomics, a research method with integrity and dynamics, corresponds to the overall regulatory effect of acupuncture and is in line with the overall concept of traditional Chinese medicine(TCM) and the concept of homeostasis. In the recent years, metabolomics has been extensively applied to the clinical and experimental study of IBD, and its potential applied value has been unanimously acknowledged by the researchers. In this article, the application status of metabolomics in acupuncture is summarized, and the research ideas to study the mechanism of acupuncture in the regulation and control of IBD by metabolomics are preliminarily explored.Acupuncture has a good therapeutic effect in treatment of inflammatory bowel diseases （IBD）, but its functional mechanism has not been systematically explained. Metabolomics is the scientific study of dynamic chemical processes involving metabolites as well as metabolic response of living organisms. Metabolomics, a research method with integrity and dynamics, corresponds to the overall regulatory effect of acupuncture and is in line with the overall concept of traditional Chinese medicine （TCM） and the concept of homeostasis. In the recent years, metabolomics has been extensively applied to the clinical and experimental study of IBD, and its potential applied value has been unanimously acknowledged by the researchers. In this article, the application status of metabolomics in acupuncture is summarized, and the research ideas to study the mechanism of acupuncture in the regulation and control of IBD by metabolomics are preliminarily explored.

关 键 词：Inflammatory Bowel Diseases Metabolomics Acupuncture-moxibustionTherapy Acupuncture Therapy Moxibustion Therapy 

分 类 号：R2-03[医药卫生—中医学]