鲜麻黄“先煎去沫”实验研究  

Experimental Study on Mechanism of Herba Ephedrae be Decoctered First and Defoamed

作　　者：蔡佳佳[1] 宋永刚[2] 宋小莉[1] 于永军[3] 沈伟[2] 

机构地区：[1]山东中医药大学基础医学院,山东济南250355 [2]山东中医药高等专科学校,山东烟台264199 [3]沧州医学高等专科学校,河北沧州061001

出　　处：《辽宁中医药大学学报》2014年第5期46-47,共2页Journal of Liaoning University of Traditional Chinese Medicine

基　　金：山东省中医药科技发展计划项目(2009-256);山东中医药大学大学生创新创业训练平台(SRT)项目(2013-40)

摘　　要：目的:通过观察麻黄"先煎去沫"与"先煎不去沫"对大鼠自主活动、发汗、心率、血压的影响,探讨麻黄先煎去沫的可能原因。方法:采用开场试验观察大鼠自主活动变化情况,采用和田-高垣氏试液涂色法检测大鼠发汗情况,采用大鼠尾动脉无创测压法检测大鼠心率血压的变化情况。结果:与麻黄先煎去沫组相比,麻黄先煎不去沫组大鼠自主活动、发汗、心率、血压指标提高(P<0.05)。结论:麻黄先煎去沫的原因可能与麻黄先煎不去沫提高大鼠自主活动、发汗、心率、血压有关,该研究为麻黄"先煎去沫"的煎煮方法提供了理论依据。Objective： The experiment is to find out the reanson why the first-decoctered Herba Ephedrae defoamed and why not defoamed. We want to study the possible different effects through the observation of those two groups on spontaneous activity, sweating, heart rate, blood pressure of rats. Methods ： The method of Opening Test was used to observe the changes in autonomic activities of rats. Through hotana high-woon＇s solution was used to observe the effect of transpiration. The method of rat tail pulses noninvasive measurement was used to test the change of heart rate and blood pressure of rats. Results ： Compared with the group of first-decoctered and defoamed Herba Ephedrae decoction, first-decoctered and undefoamed Herba Ephedrae Decoction can enhance the numerical valu on autonomic activities, Khan points, heart rate and blood pressure of rats. Conclusion ： Through the experimnet, we find out that the Herba Ephedrae Decoction first-decoctered and defoamed will enhance the numerical valu autonomic activities, rise the blood pressure and accelerate the sweating and the heart rate. The study provides a theoretical basis for the decocting method of Herba Ephedrae and preliminarily proves the mechanism of the Ephedra Decoction first-decoctered and defoamed.

关 键 词：麻黄 煎法 先煎去沫 实验研究 

分 类 号：R285.5[医药卫生—中药学]