过敏性紫癜患儿伴胰腺受累的临床特征及与其他系统关系分析  

Clinical characteristics of pancreas damage in children with Henoch-Sch（o）nlein purpura

作　　者：殷朝阳[1] 陈瑶[1] 唐晓芳[1] 

机构地区：[1]陕西省商洛市中心医院儿科,726000

出　　处：《中国医师进修杂志》2014年第12期34-36,共3页Chinese Journal of Postgraduates of Medicine

摘　　要：目的 探讨过敏性紫癜（HSP）患儿伴胰腺受累的临床特征,并分析与其他系统受累的关系.方法 回顾性分析2008年2月至2013年7月206例HSP患儿的临床资料,检测血、尿淀粉酶,B超观察患儿胰腺形态,观察患儿皮肤、关节、消化道、肾脏受累的临床特征,分析患儿胰腺受累与其他系统受累的关系.结果 206例HSP患儿中伴胰腺受累58例,其中男31例,女27例.58例HSP伴胰腺受累的患儿均行胰腺B超检查,无一例伴胰腺水肿及结构改变回声.206例患儿中伴消化道受累126例,其中50例（39.7％,50/126）出现胰腺受累（血、尿淀粉酶升高）;未伴消化道受累的80例患儿中仅有8例（10.0％,8/80）发生胰腺受累.HSP伴消化道受累患儿与未伴消化道受累患儿胰腺受累发生率比较差异有统计学意义（x2=14.355,P＜0.01）.混合型HSP患儿胰腺受累发生率[31.8％（55/173）]显著高于单纯型[9.1％（3/33）],差异有统计学意义（x2=18.292,P＜0.01）.HSP伴胰腺受累患儿住院时间为6～38 （10.39±6.80）d;不伴胰腺受累患儿住院时间为4～ 18（8.51±3.42）d,二者住院时间比较差异无统计学意义（t=5.790,P＞0.05）.结论 HSP患儿可伴胰腺受累,伴消化道受累及病变累及多系统的患儿更易伴胰腺受累.Objective To explore the clinical characteristics of pancreas damage in children with Henoch-Schonlein purpura （HSP）. Methods The clinical data of 206 HSP patients was analyzed from February 2008 to July 2013. The serum and urine example was detected by the automatic biochemical analyzer and the clinical characteristics of them was analyzed. The pancreatic morphology of patients was observed by type-B ultrasonic, and the clinical feature of skin ,joints, digestive tract and kidney damage were observed. The relationship between pancreas damage and other systems damage was analyzed. Results There was 58 cases suffering from pancreas damage in 206 HSP children：31 cases were male, 27 cases were female. There was no patients with pancreatic edema and deformation of structure in 58 patients. The incidence of pancreas damage with HSP combined with abdominalgia patients was 39.7% （50/126）,which was obviously higher than that in the patients without abdominalgia 10.0% （8/80）（ X2 = 14.355 ,P 〈 0.01 ）. The incidence of pancreas damage in mixed type of HSP [ 31.8 % （55/173）] was significantly higher than that in simple type of HSP [ 9.1% （3/33）] （X2 = 18.292,P 〈 0.01 ）. The mean hospital stay of the HSP patients with pancreas damage was 6 - 38 （ 10.39 ± 6.80） d,while without pancreas damage was 4 - 18 （8.51 ± 3.42） d, and there was no significant difference （t = 5.790,P 〉 0.05）. Conclusions The HSP children usually combine with pancreas damage. If they have abdominalgia and multi-system damage, they are more likely to be accompanied with pancreas damage, which should be paid more attention.

关 键 词：紫癜 过敏性 胰腺 儿童 体征和症状 

分 类 号：R725.5[医药卫生—儿科]