炎性因子在慢性阻塞性肺疾病气道炎症中的作用  

Role of inflammatory cytokines in airway inflammation in chronic obstructive pulmonary disease

作　　者：汪新龙[1] 刘朝晖[1] 

机构地区：[1]广州医科大学附属广州市第一人民医院呼吸科,510180

出　　处：《国际呼吸杂志》2014年第9期687-692,共6页International Journal of Respiration

摘　　要：COPD是一种以气道慢性炎症为特征之一的慢性呼吸系统疾病，气道炎性反应在COPD占有重要作用。炎性细胞因子是机体内最重要的一类细胞因子，多种炎性细胞因子参与气道炎症的病理生理机制，对肺组织和支气管产生损害，并发肺外效应。在COPD的自然病程中存在炎性细胞因子网络系统，调控COPD的气道炎症的发生发展。Chronic obstructive pulmonary disease （COPD） is a chronic respiratory disease that characterized by chronic airway inflammatory reaction, airway inflammation plays an important role in C（）PD. Inflammatory cytokines is one of the most important cytokines, there are many inflammatory cytokines in pathological and physiological mechanism of airway inflammation,caused damage to lung and bronchus,and extrapulmonary effects. There is a inflammatory cytokines network system in the natural course of COPD, and regulate the occurrence and development of airway inflammation in COPD.

关 键 词：慢性阻塞性肺疾病 炎性因子 气道炎症 研究进展 

分 类 号：R563.9[医药卫生—呼吸系统]