基于CNKI的糖尿病脑梗死证候要素及靶位研究文献分析  

Study of Syndrome Elements and Target Sites of Diabetic Cerebral Infarction Based on CNKI

作　　者：刘苇苇[1] 黄静[1] 倪青[1] 

机构地区：[1]中国中医科学院广安门医院,北京100053

出　　处：《中国中医药信息杂志》2014年第5期15-17,20,共4页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：北京市科技计划(D08050703020802)

摘　　要：目的探讨糖尿病脑梗死证候、证候要素及靶位分布规律。方法检索中国期刊全文数据库(CNKI)2003年1月-2013年10月的全部文献,从符合研究标准的22篇2550例文献病例中提取证候,并进行整理规范,分析糖尿病脑梗死的证候、证候要素及靶位。结果 2550例糖尿病脑梗死患者共有证候15种,其中痰瘀阻络659例(25.84%)、痰热腑实445例(17.45%)、风痰瘀阻366例(14.35%)、气虚血瘀341例(13.37%);共涉及证候要素10个,其中痰证1588例(62.27%)、血瘀证1026例(40.24%)、气虚证649例(25.45%)、阴虚证539例(21.14%);涉及靶位7个,主要病位为肝(2502例,98.12%)、脾(2194例,86.04%)、肾(2096例,82.20%)、脑(1026例,40.24%)。结论痰浊、血瘀、气虚、阴虚是糖尿病脑梗死主要的证候要素。痰瘀阻络、痰热腑实、风痰瘀阻、气虚血瘀是糖尿病脑梗死常见的证型。糖尿病脑梗死的病位主要在肝,涉及脾、肾、脑,其核心病机是气阴亏虚、痰瘀阻络。Objective To investigate the syndromes, syndrome elements and target sites of diabetic cerebral infarction. Method Firstly, literatures were searched from January 2003 to October 2013 in China Academic Journals Database （CNKI） retrieval system, then a database of 22 eligible articles was established. Syndromes of diabetic cerebral infarction were extracted from the database, then syndromes, syndrome elements and target sites were analyzed. Results Totally 2550 cases of diabetic cerebral infarction were concerned with 15 syndromes, including 659 cases of stagnation of phlegm and blood （25.84%）, 445 cases of stagnation of phlegm-heat （17.45%）, 366 cases of wind-phlegm syndrome （14.35%） and 341 cases of qi deficiency and blood stasis （13.37%）. There were 10 syndrome elements in the 2550 cases, of which 1588 cases with phlegm （62.27%）, 1026 cases with blood stasis （40.24%）, 649 cases with qi deficiency （25.45%） and 539 cases with yin deficiency （21.14%）. And seven target sites were encompassed, the highlights of which included 2502 cases of liver （98.12%）, 2194 cases of spleen （86.04%）, 2096 cases of kidney （82.20%） and 1026 cases of brain （40.24%）. Conclusion The important syndrome elements of diabetic cerebral infarction were phlegm, blood stasis, qi deficiency and yin deficiency. The four major syndromes comprising stagnation of phlegm and blood, stagnation of phlegm-heat, wind-phlegm syndrome and qi deficiency and blood stasis were concluded, mainly affected the liver, spleen, kidney and brain. And there were two fundamental pathogenesis in diabetic cerebral infarction：qi and yin deficiency, phlegm and blood stasis.

关 键 词：糖尿病脑梗死 证候 证候要素 靶位 

分 类 号：R2-05[医药卫生—中医学] R277.733.3