药物洗脱支架术后极晚期血栓形成原因及防治进展  

Causes and progress of prevention and treatment for very late stent thrombosis after drug-eluting stent implantation

作　　者：王春玲 

机构地区：[1]江苏泰州第四人民医院心内科,江苏泰州225300

出　　处：《心血管康复医学杂志》2014年第2期221-224,共4页Chinese Journal of Cardiovascular Rehabilitation Medicine

摘　　要：药物洗脱支架能有效减少支架再狭窄率和靶血管的再次血运重建,但与金属裸支架相比,药物洗脱支架极晚期血栓(VLST)发生率呈上升趋势。研究显示药物洗脱支架术后再内皮化延迟、抗血小板药物抵抗、PCI操作技术与晚期血栓形成有密切相关。本文就VLST形成原因、危险因素及防治策略作以下综述。Drug-eluting stent can effectively decrease stent restenosis rate and revascularization of target vessels,but compared With bare-metal stent, there Was an increasing trend in incidence rate of very late stent thrombosis （VLST）.Some study indicated that delayed re-endothelialization,anti-platelet drug resistance after drug-eluting stent thrombosis after drug-eluting stent implantation and operation technique of percutaneous coronary intervention （PCI）Were closely related to late thrombosis.This article made folloWing overvieW on cause,risk factors and pre-ventive and therapeutic strategy of VLST.

关 键 词：血栓形成 支架 血小板聚集抑制剂 

分 类 号：R541.4[医药卫生—心血管疾病]