痰热清对ICU铜绿假单胞菌肺部感染的临床研究  

Clinical research of pseudomonas aeruginosa lung infection in ICU

作　　者：刘瑶[1] 马晓俞 徐航[1] 陈淑萍[1] 于湘友[1] 

机构地区：[1]新疆医科大学第一附属医院重症医学科,新疆乌鲁木齐830054

出　　处：《临床肺科杂志》2014年第6期974-976,共3页Journal of Clinical Pulmonary Medicine

基　　金：乌鲁木齐市科学技术项目(No Y111310024)

摘　　要：目的：探讨痰热清注射液在铜绿假单胞菌肺部感染中的作用。方法对我院2012年1月-2013年3月ICU铜绿假单胞菌肺部感染患者随机分为标准组和处理组，标准组按照常规治疗法治疗（抗菌药物应用根据病原微生物培养及药敏结果确定），处理组在常规治疗的基础上辅助痰热清注射液治疗。结果处理组的APACHEⅡ评分、SOFA评分较标准组下降更明显；其ICU住院天数、28天内抗生素使用天数、机械通气的天数均明显低于标准组。两组28天、90天病死率无明显差异（ P〉0．05）。结论痰热清注射液具有协同抗菌作用，对治疗铜绿假单胞菌肺部感染具有较好的疗效。Objective To investigate the effect of Tanreqing injection in the treatment of pseudomonas aeruginosa lung infection in ICU. Methods Patients with pseudomonas aeruginosa pneumonia were randomly divided into the treatment group and the control group. All patients were treated with conventional therapy, and the treatment group was given Tanreqing injection. Results APACHEⅡ score and SOFA score in the treatment group decreased more significantly than in the control group. Duration of ICU stay, antibiotic use within 28 days, and days of mechan-ical ventilation were significantly shorter in the treatment group than in the control group. There was no significant difference in mortality between the two groups （P〉0. 05）. Conclusion Tanreqing injection has synergistic antibac-terial effect, which is effective in the treatment of pseudomonas aeruginosa pneumonia.

关 键 词：铜绿假单胞菌 肺部感染 痰热清注射液 

分 类 号：R259[医药卫生—中西医结合]