SP825型大孔树脂对栀子苷的吸附性能考察  

Investigation of Static Absorption Properties for Geniposide with SP825 Macroporous Resin

作　　者：丁玲[1] 高俊峰[2] 张鹏[2] 刘建勋[2] 

机构地区：[1]北京中医药大学,北京100029 [2]中国中医科学院西苑医院基础医学研究所,北京100091

出　　处：《中国实验方剂学杂志》2014年第10期40-44,共5页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家自然科学基金项目(30772755;81073060);国家科技重大专项(2009ZX09103-317)

摘　　要：目的:优选栀子苷的大孔树脂吸附条件,考察栀子苷在SP825型大孔树脂的吸附动力学、热力学过程。方法:在单因素试验基础上,以栀子苷吸附率为指标,采用响应面法优化栀子苷的吸附条件,确定SP825型树脂吸附栀子苷的等温吸附模型、动力学模型和热力学参数。结果:最佳吸附条件为上样液质量浓度83 g·L-1,pH 2.79;最大吸附量247 mg·g-1。Freundlich方程可很好地拟合等温吸附热力学过程,拟二级方程可很好地描述吸附动力学过程。结论:栀子苷的吸附过程为自发放热反应,且低温有利于吸附,吸附速率主要由液膜扩散控制。Objective： To optimize adsorption conditions of geniposide on SP825 macroporous resin and investigate its adsorption equilibrium,thermodynamics and kinetics. Method： Based on single factor tests,response surface methodology was adopted to optimize adsorption conditions of geniposide with adsorption rate as index,isotherm adsorption model,kinetic curve and thermodynamic parameters of geniposide on SP825 resin were measured. Result： Optimum adsorption conditions were as follows：the concentration of sample solution 83 g·L^-1,pH of 2.79;The maximum adsorption capacity was 247 mg·g^-1.Adsorption equilibrium was well fitted by Freundlich formula,and kinetics process could be formulated by pseudo-second equation. Conclusion： Adsorption of geniposide was an spontaneous exothermic process,which could benefit from low temperature,adsorption rate was mainly controlled by liquid membrane diffusion.

关 键 词：栀子苷 大孔吸附树脂 响应面分析法 吸附动力学 吸附热力学 单因素试验 

分 类 号：R283.6[医药卫生—中药学] R284.2[医药卫生—中医学]