冠状动脉介入联合心脏再同步化治疗缺血性心肌病顽固性心力衰竭的临床疗效  

Clinical Observation on Coronary Intervention with Cardiac Resynchronization Therapy for Treatment of Intractable Heart Failure in Ischemic Cardiomyopathy

作　　者：付敏[1] 师聪红[1] 张宝红[1] 

机构地区：[1]内蒙古包头市第四医院

出　　处：《中西医结合心脑血管病杂志》2014年第3期259-260,共2页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

摘　　要：目的观察冠状动脉介入治疗联合心脏再同步化治疗缺血性心肌病顽固性心力衰竭临床效果,并探讨其安全性。方法选取2010年4月—2012年6月来我院心血管科就诊的缺血性心肌病顽固性心力衰竭患者60例,随机分为试验组和对照组,各30例。试验组给予冠状动脉介入治疗联合心脏再同步化治疗,对照组仅给予冠状动脉介入治疗。观察治疗效果及随访并发症发生情况。结果治疗后试验组有效率为90.00%,对照组有效率为86.66%,两组差异无统计学意义(P>0.05);试验组死亡1例,再发心肌梗死3例,脑栓塞1例,心律失常4例;对照组死亡5例,再发心肌梗死8例,脑栓塞4例,心律失常10例,差异具有统计学意义(P<0.05)。结论冠状动脉介入治疗联合心脏再同步化治疗缺血性心肌病顽固性心力衰竭较单独应用冠状动脉介入治疗近期临床效果相近,两者都可明显改善心功能,提高生活质量;联合治疗方案可提高心衰患者远期生活质量。Objective To observe the clinical effect of coronary intervention with cardiac resynchronization therapy for treatment of intractable heart failure of ischemic cardiomyopathy(IHFIC).Methods Sixty patients with IHFIC were randomly divided into two groups:Experiment group(n=30)treated with coronary intervention and cardiac resynchronization therapy,and control group(n=30) treated with coronary intervention.Clinical effects and complications were observed.Results The effective rate was 90%in experiment group and 86.66%in control group(P>0.05).There were 1died,3recurrent myocardial infarction(MI),1cerebral embolism, and 4arrhythmia in experiment group.There were 5died,8recurrent MI,4cerebral embolism,and 10arrhythmia in control group(P<0. 05).Conclusion Coronary intervention with cardiac resynchronization therapy had a similar short-term clinical effect with coronary intervention alone for treatment of IHFIC.Both could obviously improve heart function and life equality.Coronary intervention with cardiac resynchronization therapy had a better long term effect with fewer complications and lower death rate.

关 键 词：顽固性心力衰竭 心肌病 介入治疗 心脏再同步化治疗 

分 类 号：R541.6[医药卫生—心血管疾病] R256.2[医药卫生—内科学]