二醋酸碘苯促进的芳酮类化合物羰基邻位乙酰化反应研究  

α-Acetoxylation of Aromatic Ketones Mediated by Iodobenzene Diacetate

作　　者：谭丽泉[1] 刘卫兵[1] 黄敏[1] 余梅[1] 

机构地区：[1]广东石油化工学院化学与生命科学学院,茂名525000

出　　处：《有机化学》2014年第4期817-820,共4页Chinese Journal of Organic Chemistry

基　　金：广东省自然科学基金(No.S2012040007868)资助项目~~

摘　　要：以苯乙酮类化合物为原料,氧化锌(ZnO)为催化剂,二醋酸碘苯为氧化剂,通过对羰基邻位饱和sp3-C—H键的氧化与乙酰化,成功的构建出了α-乙酸基苯乙酮类衍生物,其结构经1H NMR和13C NMR得到了确认,并提出了可能的反应机理.This paper reports a simple method for the synthesis of a-acetoxyacetophenone derivatives from acetophenones using ZnO as a catalyst and iodobenzene diacetate as an oxidant. This transformation undergoes two processes： the oxidation of saturated sp3-C--H bond and the acetoxylation of C = C bond. The structures of products were confirmed by IR, I H NMR and 13C NMR. In addition, a possible reaction mechanism was proposed.

关 键 词：二醋酸碘苯 乙酰苯酮 饱和sp3-C—H键氧化 乙酰化 

分 类 号：O621.25[理学—有机化学]