A brief review of recent advances in stem cell biology  

作　　者：Jinhui Chen Libing Zhou Su-yue Pan 

机构地区：[1]Stark Neuroscience Research Institute and Department of Neurological Surgery, Indiana University School of Medicine [2]Guangdong-Hongkong-Macao Institute of CNS Regeneration (GHMICR), Jinan University [3]Department of Neurology, Nanfang Hospital, Southern Medical University

出　　处：《Neural Regeneration Research》2014年第7期684-687,共4页中国神经再生研究（英文版）

基　　金：supported by NIH/NINDS R01-NS043246,P30-NS045758;the International Spinal Research Trust(STR-100);the Ohio State University College of Medicine

摘　　要：Stem cells have the remarkable potential to develop into many different cell types, essentially with- out limit to replenish other cells as long as the person or animal is still alive, offering immense hope of curing Alzheimer＇s disease, repairing damaged spinal cords, treating kidney, liver and lung diseases and making damaged hearts whole. Until recently, scientists primarily worked with two kinds of stem cells from animals and humans： embryonic stem cells and non-embryonic ＂somatic＂ or ＂adult＂ stem cells. Recent breakthrough make it possible to convert or ＂reprogram＂ specialized adult cells to assume a stem stem-like cells with different technologies. The review will briefly dis- cuss the recent progresses in this area.Stem cells have the remarkable potential to develop into many different cell types, essentially with- out limit to replenish other cells as long as the person or animal is still alive, offering immense hope of curing Alzheimer＇s disease, repairing damaged spinal cords, treating kidney, liver and lung diseases and making damaged hearts whole. Until recently, scientists primarily worked with two kinds of stem cells from animals and humans： embryonic stem cells and non-embryonic ＂somatic＂ or ＂adult＂ stem cells. Recent breakthrough make it possible to convert or ＂reprogram＂ specialized adult cells to assume a stem stem-like cells with different technologies. The review will briefly dis- cuss the recent progresses in this area.

关 键 词：stem cell adult stem cell embryonic stem cell somatic cell nuclear transfer induced plu-ripotent stern cell stimulus-triggered acquisition of pluripotency 

分 类 号：R329.2[医药卫生—人体解剖和组织胚胎学]