837株鲍曼不动杆菌感染临床分布及耐药性调查  

INVESTIGATION ON CLINICAL DISTRIBUTION AND DRUG RESISTANCE OF 837 STRAINS OF Acinetobacter baumaniis

作　　者：王清[1,2] 刘琪[1,2] 

机构地区：[1]浙江省绍兴市人民医院 [2]浙江大学绍兴医院,浙江绍兴312000

出　　处：《中国消毒学杂志》2014年第4期377-379,共3页Chinese Journal of Disinfection

基　　金：绍兴市科技计划项目(2012B70058)

摘　　要：目的了解住院患者鲍曼不动杆菌感染的临床分布及其对21种常用抗菌药物药敏试验结果,更好地指导临床用药。方法采用回顾性调查方法,收集某医院2012年全年临床送检标本检出的鲍曼不动杆菌资料,进行临床分布和药敏试验结果分析。结果本年度从住院患者感染标本中共分离鲍曼不动杆菌837株,其中有85.5%的菌株分离自呼吸道痰液标本。鲍曼不动杆菌感染患者主要分布于该医院重症监护病房,其构成比为62.6%。临床分离的鲍曼不动杆菌除对多粘菌素B敏感外,对其他常用抗菌药物均具有一定的耐药性,其中对氨曲南、四环素、哌拉西林的耐药率较高,对美洛培南和亚胺培南等碳青霉烯类的耐药率已接近70%。结论该医院鲍曼不动杆菌感染患者主要集中在ICU,该菌对临床常用抗菌药物已普遍耐药,应加强监控和抗菌药物管理。Objective To investigate the clinical distribution and drug resistance to 21 kinds of commonly used antimi- crobial agents of Acinctobacter Baumanniis in patients and to guide for clinical. Methods Retrospective survey was used to analyze the clinical distribution and drug resistance of Acinctobacter baumaniis from clinical specimens of each department in our hospital in year 2012. Results A total of 837 strains of A. baumannii were isolated in patients this year, and were mainly isolated from sputum（85.5% ）. The patients who infected were mainly from ICU（62.6% ）. The drug susceptibility results showed that the commonly used antimicrobial agents have certain resistance except PMB. The drug resistance rates to AZT,TET,PIPC were higher. Penicillium carbon alkene antimicrobial resistance was also high, the drug resistance of Meropenem and Imipenem was close to 70%. Conclusion The patients who infected with A. baumannii were mainly from ICU in our hospital. The bacteria against to commonly used antimicrobial agents has been widespread resistance. It is nec- essary to strengthen the surveillance and management of antibacterial drugs.

关 键 词：医院感染 鲍曼不动杆菌 耐药性 监测 

分 类 号：R378[医药卫生—病原生物学]