老年性布鲁杆菌病性脊椎炎38例临床诊疗分析  

Diagnosis and treatment of senile brucellosis spondylitis

作　　者：杨新明[1] 石蔚[1] 孟宪勇[1] 胡长波[1] 章鹏[2] 王耀一[1] 贾永利[1] 胡振顺[1] 赵御森[1] 

机构地区：[1]河北北方学院附属第一医院,河北省张家口075000 [2]河北北方学院研究生院

出　　处：《中华全科医师杂志》2014年第5期386-388,共3页Chinese Journal of General Practitioners

基　　金：基金项目：2013年河北省医学重点学科跟踪项目（GL201321）;2013年河北省省级重大医学科研课题（zd2013049）;张家口市2010年科学技术与发展指令计划资助项目（1012010D-1）

摘　　要：2002年1月至2012年3月共收治38例老年布鲁杆菌病性脊椎炎患者，入院前均误诊为脊柱结核。入院后，根据流行病史、临床表现、实验室检查、影像学检查与病理学检查结果，得到确诊。治疗后12个月随访，17例经规范化药物治疗治愈；21例行手术治疗，治愈19例，改善2例。老年性布鲁杆菌病性脊椎炎具有血清学及病理学特征性表现，诊断标准的制定有助于提高诊断率，减少误诊率，规范化药物治疗具有较好的治愈率，适时手术干预可提高临床疗效。A total of 38 cases of senile brucella spondylitis disease at our hospital during January 2002 and March 2012 were analyzed. After admission, all of them were definitely diagnosed on the basis of epidemiological history, clinical manifestations, laboratory tests, imaging and pathological examinations. Over a follow-up period of 12 months, 17 cases were cured after standardized drug treatment. Among 21 surgical cases, there were curing （n = 17 ） and improving （n = 2 ）. Senile brucellosis spondylitis has distinct serological and pathological characteristics. And formulating the diagnostic criteria may improve its diagnostic rate and reduce its misdiagnostic rate. And standardized drug therapy achieves a better curing rate and a proper timing of surgical intervention improves its clinical outcomes.

关 键 词：布鲁杆菌病 脊椎炎 

分 类 号：R516.7[医药卫生—内科学]