尿酸在妊高征患者监测中的临床应用价值  

Clinical value of uric acid detection in patients with pregnancy-induced hypertension

作　　者：许盛芳[1] 文辉彬 柳玲[2] 

机构地区：[1]四川省内江市第二人民医院妇产科,四川内江641100 [2]深圳市龙岗区横岗人民医院妇产科,广东深圳518100

出　　处：《海南医学院学报》2014年第6期815-817,821,共4页Journal of Hainan Medical University

基　　金：深圳市龙岗区科技计划项目(YS2011057)~~

摘　　要：目的:研究妊高征孕妇机体尿酸的变化情况,探讨尿酸在妊高征患者监测中的临床价值。方法:选择86例正常孕妇为对照组,167例不同严重程度妊高征孕妇作为病例组,比较两组尿酸水平及不同尿酸水平妊高征患者的围产儿情况。结果:不同严重程度妊高征各组及对照组收缩压、舒张压及尿酸血清水平均有统计学差异(P<0.05);妊高征患者尿酸与收缩压、舒张压呈正相关(r=0.516、0.427,P<0.05);不同尿酸水平妊高征围产儿新生儿体重、新生儿Apgar评分、围生儿病死数均有统计学差异(P<0.05),产妇剖宫产率、早产发生率也均有统计学差异(P<0.05)。结论:妊高征血清尿酸浓度与患者病情严重程度相关,对围产儿结局有一定指示作用。Objective： To study the change in uric acid of pregnancy-induced hypertension women. Methods.. A total of 86 normal pregnant women were selected as the control group, and 167 pregnancy-in duced hypertension women were selected as observation group. Uric acid was detected and compared. And perinatal infant condition was compared among women with different levels of uric acid. Results： There were significant differences in systolic blood pressure, diastolic blood pressure and uric acid serum levels a- mong women with different severity of pregnancy-induced hypertension （P〈0.05）. Uric acid was positively related with systolic blood pressure （r=0. 516, P〈0.05） and diastolic blood pressure （r=0. 427, P〈0.05）. There were significant differences in birth weight, neonatal Apart score, death of newborns among women with different severity of pregnancy induced hypertension （P〈0.05）. The differences in cesarean section rate, incidence of preterm birth were statistically significant （P〈0. 05）. Conclusion： In pregnancy-induced hypertension women, serum uric acid concentrations is related with the severity of the disease, and it is meaningful in perinatal outcome.

关 键 词：尿酸 妊高征 围产儿结局 新生儿体重 APGAR评分 

分 类 号：R714.25[医药卫生—妇产科学]