喜炎平注射液致不良反应143例文献分析  

Literature analysis of 143 cases of adverse drug reactions of Xiyanping injection

作　　者：刘玉波[1] 

机构地区：[1]天津市南开医院,天津300100

出　　处：《天津药学》2014年第2期41-43,共3页Tianjin Pharmacy

摘　　要：目的:探讨喜炎平注射液致不良反应的一般规律及特点,为安全、合理使用该药提供建议。方法:对2002年1月—2013年12月国内医药期刊报道的143例喜炎平注射液不良反应病例进行分类统计分析。结果:喜炎平注射液所致不良反应与性别无关,多发生于<10岁年龄组,其出现时间多为用药后的前30 min内。不良反应主要表现为速发性变态反应,其中以皮肤、呼吸系统、心血管系统发生率最高,有1例死亡病例。结论:临床医师、药师应了解喜炎平注射液所致不良反应的规律和特点,加强其应用的监测,以减少不良反应的发生。Objective： To explore the general pattern and characteristics of adverse drug reactions（ADR） induced by Xiyanping injection so as to provide references for clinical rational drug use. Methods： A statistical analysis was conducted on 143 Xiyanping injection induced ADR cases reported in domestic medical journals between Jan. 2002 and Dec 2013. Results： ADR of Xiyanping were independent of patient＇s sex, and mostly occurred in the 〈 10 group. They usually occurred in the first 30 minutes after taking the drug. Clinical manifestations of ADR were simple, mainly were immediate allergy,especially in integumentary, respiratory and cardiovascular system, one case was dead. Conclusion： Doctors and pharmacists should know the pattern and characteristics of ADR, and the use of Xiyanping injection should be under strict monitoring to reduce the occurrence of serious ADR.

关 键 词：喜炎平注射液 不良反应 文献分析 

分 类 号：R969.3[医药卫生—药理学]