经尿道钬激光联合吉西他滨灌注治疗腺性膀胱炎的疗效观察  

Clinical effect of transurethral holmium laser combined with intravesical instillation of gemcitabine on treatment of cystitis glandularis

作　　者：朱宏刚[1] 韩明[1] 龚仁杰[1] 姚兵[1] 邱劲[1] 胡波勇[1] 王瑜[1] 刘庆[1] 余晓晖[1] 

机构地区：[1]湖北省新华医院泌尿外科,湖北武汉430015

出　　处：《实用医院临床杂志》2014年第3期117-118,共2页Practical Journal of Clinical Medicine

摘　　要：目的：探讨经尿道钬激光联合吉西他滨灌注治疗腺性膀胱炎（ cystitis glandularis ，CG）的疗效。方法52例CG患者经活组织检查、膀胱镜检等方法确诊后，均行经尿道钬激光切除，术后采取吉西他滨膀胱灌注化疗进行治疗。结果52例患者获得6～36个月随访，33例治愈，8例好转，4例6～12个月复发，均未发生癌变。结论经尿道钬激光切除联合术后吉西他滨膀胱内灌注治疗CG术后复发率低，并发症少，安全性高。Objective To investigate the clinical efficacy of transurethral holmium laser combined with intravesical instillation of gemcitabine in treatment of cystitis glandularis .Methods Based on biopsy and cystoscopy ,52 cases of patients were diagnosed as cystitis glandularis .With the agreement of families ,all patients were treated with this type of surgery .Results The all patients were fol-lowed up for 6 to 36 months.Among them,33 cases were cured and 8 cases improved.There were 4 cases with recurrence during 6 to 12 months ,but not becoming cancerous .Conclusion Transurethral holmium laser resection combined with postoperative intravesical gem-citabine therapy can effectively reduce the recurrence of glandular cystitis with fewer side -effects and more safety .

关 键 词：钬激光 吉西他滨 腺性膀胱炎 疗效观察 

分 类 号：R649.3[医药卫生—外科学]