高脂血症对直肠癌开腹及腹腔镜手术合并症的影响  

Effects study of hyperlipidemia on postoperative complications in patients of rectal cancer with different surgical

作　　者：吴为明[1] 陈凤娜 

机构地区：[1]宁波大学附属医院肛肠外科,浙江宁波315020 [2]宁波市中医院六病区,浙江宁波315012

出　　处：《中国医药导报》2014年第13期51-54,共4页China Medical Herald

摘　　要：目的探讨高脂血症对直肠癌不同手术方式合并症的影响。方法选择2010年1月～2012年12月宁波大学附属医院直肠癌患者142例，按血脂水平及手术方式分组：高脂血症组74例，非高脂血症组68例：开腹手术组65例，腹腔镜手术组77例；开腹手术组中高脂血症患者33例，非高脂血症患者32例；腹腔镜手术组中高脂血症患者41例，非高脂血症患者36例。比较上述各组手术时间、术中出血量、恢复进食时间、住院时间、拔除引流管时间、并发症的发生率。结果①高脂血症组术中出血量多于非高脂血症组，术后恢复进食时间、住院时间及拔除引流管时间长于非高脂血症组，差异均有统计学意义（P〈0．05）；高脂血症组切口脂肪液化发生率高于非高脂血症组，差异有统计学意义（P〈0．05）。②腹腔镜手术组手术时间、术中出血量、恢复进食时间、住院时间、拔除引流管时间均低于开腹手术组，差异均有统计学意义（P〈0．05）。并发症比较，腹腔镜手术组切口脂肪液化发生率低于开腹手术组，差异有统计学意义（P〈0．05）。③开腹手术组中高脂血症患者术中出血量多于非高脂血症患者，术后恢复进食时间、住院时间、拔除引流管时间长于非高脂血症患者，差异均有统计学意义（P〈0．05）。开腹手术组高脂血症患者切口脂肪液化发生率高于非高脂血症患者，差异有统计学意义（P〈0．05）。④腹腔镜手术组中高脂血症高脂血症患者术中出血量多于非高脂血症患者，差异有统计学意义（P〈0．05）；其余指标差异均无统计学意义（P〉0．05）。结论高脂血症可增加直肠癌手术出血量、延长恢复时间和增加并发症发生率：腹腔镜手术有利于术后恢复，是更适合高脂血症患者的术式。Objective To investigate the effects of hyperlipidemia on postoperative complications in patients of rectal cancer with different surgical. Methods 142 patients with rectal cancer in Affiliated Hospital of Ningbo University from January 2010 to December 2012 were selected and divided into different groups according to serum lipid levels and operation methods： 74 cases into hyperlipidemia group, 68 cases into non-hyperlipidemia group; 65 cases into laparoto- my group, 77 cases into laparoscope group. In laparotomy group, 32 cases of normal cholesterol, 33 cases of hyperlipi- demia were found; in laparoscopic group, 36 cases of normal cholesterol, 41 cases of hyperlipidemia were found. Peri- operative indicators such as operative time, blood loss volume, postoperative recovery time for eating, hospital stay were compared. Results ①Blood loss volume in hyperlipidemia group was higher than that in non-hyperlipidemia group; postoperative recovery time for eating, hospital stay, removal time of drainage tube in hyperlipidemia group was longer than that in non-hyperlipidemia group, the differences were statistically significant （P 〈 0.05）. Occurrence rate of oper- ative incision healing in hyperlipidemia group was higher than that in non-hyperlipidemia group, the difference was statistically significant （P 〈 0.05）. ②The operation time, blood loss volume, postoperative recovery time for eating, hos- pital stay, removal time of drainage tube in laparoscope group were all lower than those in laparotomy group, the dif- ferences were statistically significant （P 〈 0.05）. Occurrence rate of operative incision healing in laparoscope group was lower than that in laparotomy group, the differences were statistically significant （P 〈 0.05）. ③The blood loss volume in patients with hyperlipemia in laparotomy group was higher than that in patients without hyperlipemia; the postoperative recovery time for eating, hospital stay, removal time of drainage tube in patients with hyperlipemia in laparotomy gr

关 键 词：高脂血症 直肠癌 开腹手术 腹腔镜手术 

分 类 号：R656[医药卫生—外科学]