超声引导下细针穿刺细胞学检查在坏死性淋巴结炎诊断中的应用  

Application of ultrasound-guided aspiration cytology combined with the liquid based cytology in the diagnosis of necrotizing lymphadenitis

作　　者：洪练青[1] 王新方[2] 王雄威[1] 王建东[3] 

机构地区：[1]南京中医药大学附属南京市中西医结合医院病理科,江苏南京210014 [2]南京中医药大学附属南京市中西医结合医院超声科,江苏南京210014 [3]南京军区总医院病理科,江苏南京210002

出　　处：《东南国防医药》2014年第2期138-140,共3页Military Medical Journal of Southeast China

基　　金：南京市医学科技发展项目(YKK11068)

摘　　要：目的探讨坏死性淋巴结炎在超声引导下细针穿刺细胞学检查中的特点。方法采用一次性10 ml注射器及7号细针(外径7 mm),经皮超声引导下对体表可疑坏死性淋巴结进行穿刺抽吸,所得标本进行常规涂片,针头内残余标本注入泰普提供的细胞专用固定保存液中,应用液基细胞薄层制片技术(LCT)制片。结果细针穿刺细胞学诊断坏死性淋巴结炎139例,其中42例进行淋巴结活检,有37例经组织病理学证实为坏死性淋巴结炎、3例为淋巴结淋巴组织增生、1例为淋巴结结核、1例为经典型霍奇金淋巴瘤(结节硬化型)。细胞学诊断与组织病理结果对比,准确率为88.1%。结论细针穿刺细胞学检查对坏死性淋巴结炎诊断正确率高,可减少不必要的手术活检,使患者得到及早治疗,并降低诊疗费用。Objective To explore the cytological characteristics of necrotizing lymphadenitis in ultrasound -guided aspiration . Methods The suspicious necrotic lymph nodes on the body surface were aspirated using a 10 ml disposable syringe （ diameter 7 mm） with the percutaneous ultrasound guided .Samples were used for conventional smear ,and the needle residual specimens were injected in-to fixed solution for cells .The cellular slide was prepared by a liquid based cytology test （ LCT） .Results Fine needle aspiration cytol-ogy was used in the diagnosis of necrotizing lymphadenitis in 139 cases.Among these samples ,42 cases were carried out lymph node bi-opsy,and 37 cases were histologically confirmed as necrotizing lymphadenitis ,3 cases were hyperplasia of lymphoid tissue ,1 case was tuberculosis of lymph node,and 1 case was classical Hodgkin lymphoma （nodular sclerosis type）.The accuracy rate of cytology was 88.1%compared with pathological results .Conclusion The correct diagnosis rate of necrotizing lymphadenitis with the fine needle as -piration cytology is high .This can reduce the operation for biopsy ,makes patients get early treatment ,and reduces medical expenses .

关 键 词：超声引导 针吸细胞学 坏死性淋巴结炎 液基制片 

分 类 号：R632.6[医药卫生—外科学]