黄芩中汉黄芩素的提取制备  

Extraction and Preparation of Wogonin from Radix Scutellariae

作　　者：李文娟[1] 潘馨[1] 陈晓兰[2] 陈维中[2] 廖联明[1] 

机构地区：[1]福建中医药大学,福建福州350122 [2]南京军区福州总医院第一附属医院,福建莆田351100

出　　处：《亚太传统医药》2014年第9期33-35,共3页Asia-Pacific Traditional Medicine

摘　　要：为建立制备大量高纯度汉黄芩素的方法,将中药黄芩50g用pH 5水水解12h,再用95％的乙醇提取,得到的提取物浸膏,过30～60目的聚酰胺树脂柱纯化,将含有汉黄芩素的洗脱物采用高速逆流色谱（HSCCC）进行分离.通过该方法制得汉黄芩素525mg,纯度为98.7％.To develop a method for large scale preparation of high-purity Wogonin from Radix Scutellariae. 50g of Radix Scutellariae was hydrolyzed in water （pH 5） for 12h, and then extracted with 95% ethanol. The extractum was seperated with 30 - 60 mesh polyamide resin column. Fraction with Wogonin was subjected to high-speed countercurrent chromatography （HSCCC） . 525mg Wogonin is obtained with a purity 98.7 %. Thus an effective method for preparing high-purity Wogonin was established.

关 键 词：汉黄芩素 黄芩 提取 聚酰胺柱 纯化 高速逆流色谱 

分 类 号：R284.2[医药卫生—中药学]