榄香烯注射液致药物不良反应37例文献分析  

Adverse Drug Reaction Induced by Elemene Injection:Literature Analysis of 37Cases

作　　者：徐婷[1] 钟玲[1] 杜憬生[1] 

机构地区：[1]广东省中医院,广东广州510370

出　　处：《亚太传统医药》2014年第9期126-128,共3页Asia-Pacific Traditional Medicine

摘　　要：目的:探讨榄香烯注射液不良反应的一般规律和特点。方法:检索《中国期刊全文数据库》1995-2013年中榄香烯注射液所致不良反应(ADR)的文献并对其进行统计分析。结果:37例ADR中,男、女患者分别占64.9%和35.1%,老年患者发生ADR的比例较高,ADR大多发生在首次用药及用药30min内,主要以皮肤及其附件损害(34.8%)为主,其次是呼吸(21.7%)、心血管系统(18.8%)。发生ADR患者的原患疾病主要为癌症,不良反应的治疗和预后良好。结论:临床应高度重视榄香烯注射液所致不良反应,加强用药监测,确保用药安全。Objective：To discuss the general characteristics of the ADRs induced by Elemene injection and to provide reference for rational drug use in clinic. Methods： Literature related to the ADR by induced Elemene injection reported during 19952013 retrieved from CNKI was analyzed statistically. Results：Among the 37 ADR cases, the proportions of the male and female patients were 64.9% and 35.1%. ADRs of Elemene injection often occurred in aged group. Most of the ADRs induced by Elemene injection occurred within 30 minutes after medication. The skin and addenda damage （34.8%） occupied the major part in ADR cases and followed by respiratory （21.7%） and cardiovascular system （18.8%）. The original diseases of the patients who had ADR are mainly cancer. The treatment and prognosis of adverse drug reactions is good. Conclusion ： Attention should be paid to the characteristics of adverse drug reactions induced by Elemene injection in clinical use, and the monitoring of medication should also be strengthened to ensure the safe medication.

关 键 词：榄香烯注射液 不良反应 文献分析 

分 类 号：R28[医药卫生—中药学]